http://hdl.handle.net/2027.42/78207 2013-05-24T13:22:03Z http://hdl.handle.net/2027.42/78143 Metabolic Syndrome in a Workplace: Prevalence, Co-Morbidities, and Economic Impact Schultz, Alyssa B.; Edington, Dee W. Background: Although the prevalence of metabolic syndrome has been studied in nationally representative populations, little is known about its prevalence specifically among working adults. Because corporations are often the primary payers of health-care costs in the United States, they have a vested interest in knowing the impact of metabolic syndrome in employed individuals. Methods: A total of 4188 employees (83.4% male, 92.1% Caucasian, average age 40.8 years) of a midwestern U.S. manufacturing corporation participated in a health risk appraisal and biometric screening in 2006 and also used the company's medical plan. Those with metabolic syndrome were compared to those without metabolic syndrome in terms of their 2006 health risks, health conditions, health-care costs, pharmacy costs, short-term disability costs, and a measure of on-the-job productivity loss known as presenteeism. Results: A total of 30.2% of employees met the criteria for metabolic syndrome and were more likely to also have a variety of additional health risks and health conditions compared to those without metabolic syndrome. For example, 9.4% of those with metabolic syndrome self-reported having diabetes compared to 1.4% of those without metabolic syndrome. Health-care costs, pharmacy costs, and short-term disability costs were significantly higher for those with metabolic syndrome compared to those without metabolic syndrome, and increasing numbers of metabolic syndrome health risks were associated with greater numbers of employees reporting on-the-job productivity losses (presenteeism). Conclusions: Because metabolic syndrome is prevalent among the employees of this manufacturing company and is associated with significant economic costs, employers would be wise to address the health risks of employees through health promotion programs and benefit plan designs that help individuals improve their health and receive appropriate health screenings and medical care. 2009-10-01T00:00:00Z http://hdl.handle.net/2027.42/75578 Collective Reputation and Quality Winfree, Jason A.; McCluskey, Jill J. 2005-02-01T00:00:00Z http://hdl.handle.net/2027.42/75375 Analysis of the Association between Metabolic Syndrome and Disease in a Workplace Population over Time Schultz, Alyssa B.; Edington, Dee W. Objectives:  While research has confirmed an association between metabolic syndrome (MetS) and diseases such as heart disease and diabetes, none of these studies have been conducted in a worksite population. Because corporations are often the primary payer of health-care costs in the United States, they have a vested interest in identifying the magnitude of MetS risk factors in employed populations, and also in knowing if those risk factors are associated with other health risks or medical conditions. Methods:  This study identified the prevalence of MetS risk factors and self-reported disease in employees (N = 3285) of a manufacturing corporation who participated in a health risk appraisal and biometric screening in both 2004 and 2006. Health-care costs, pharmacy costs, and short-term disability costs were compared for those with and without MetS and disease. Results:  The prevalence of MetS increased from 2004 to 2006 in this employed population. Those with MetS were significantly more likely to self-report arthritis, chronic pain, diabetes, heartburn, heart disease, and stroke. Employees with MetS in 2004 were also significantly more likely to report new cases of arthritis, chronic pain, diabetes, and heart disease in 2006. The costs of those with MetS and disease were 3.66 times greater than those without MetS and without disease. Conclusions:  MetS is associated with disease and increased costs in this working population. There is an opportunity for health promotion to prevent MetS risk factors from progressing to disease status which may improve vitality for employees, as well as limit the economic impact to the corporation. 2010-03-01T00:00:00Z http://hdl.handle.net/2027.42/73299 Generation of soluble P- and E-selectins in vivo is dependent on expression of P-selectin glycoprotein ligand-1 Bodary, P. F.; Homeister, J. W.; Vargas, F. B.; Wickenheiser, K. J.; Cudney, S. S.; Bahrou, K. L.; Öhman, M.; Rabbani, A. B.; Eitzman, D. T. 2007-03-01T00:00:00Z