Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney
dc.contributor.author | Self, Michelle | en_US |
dc.contributor.author | Lagutin, Oleg V | en_US |
dc.contributor.author | Bowling, Beth | en_US |
dc.contributor.author | Hendrix, Jaime | en_US |
dc.contributor.author | Cai, Yi | en_US |
dc.contributor.author | Dressler, Gregory R | en_US |
dc.contributor.author | Oliver, Guillermo | en_US |
dc.date.accessioned | 2014-01-08T20:34:29Z | |
dc.date.available | 2014-01-08T20:34:29Z | |
dc.date.issued | 2006-11-01 | en_US |
dc.identifier.citation | Self, Michelle; Lagutin, Oleg V; Bowling, Beth; Hendrix, Jaime; Cai, Yi; Dressler, Gregory R; Oliver, Guillermo (2006). "Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney." The EMBO Journal 25(21): 5214-5228. <http://hdl.handle.net/2027.42/102083> | en_US |
dc.identifier.issn | 0261-4189 | en_US |
dc.identifier.issn | 1460-2075 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/102083 | |
dc.publisher | John Wiley & Sons, Ltd | en_US |
dc.subject.other | Homeobox | en_US |
dc.subject.other | Mouse | en_US |
dc.subject.other | Nephrogenesis | en_US |
dc.subject.other | Six2 | en_US |
dc.subject.other | Kidney | en_US |
dc.title | Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.identifier.pmid | 17036046 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102083/1/emboj7601381-sup-0006.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102083/2/emboj7601381-sup-0002.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102083/3/emboj7601381-sup-0007.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102083/4/emboj7601381-sup-0003.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102083/5/emboj7601381.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102083/6/emboj7601381-sup-0004.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102083/7/emboj7601381-sup-0005.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/102083/8/emboj7601381-sup-0001.pdf | |
dc.identifier.doi | 10.1038/sj.emboj.7601381 | en_US |
dc.identifier.source | The EMBO Journal | en_US |
dc.identifier.citedreference | Sanchez MP, Silos‐Santiago I, Frisen J, He B, Lira SA, Barbacid M ( 1996 ) Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382: 70 – 73 | en_US |
dc.identifier.citedreference | Plachov D, Chowdhury K, Walther C, Simon D, Guenet JL, Gruss P ( 1990 ) Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development 110: 643 – 651 | en_US |
dc.identifier.citedreference | Qian J, Jiang Z, Li M, Heaphy P, Liu YH, Shackleford GM ( 2003 ) Mouse Wnt9b transforming activity, tissue‐specific expression, and evolution. Genomics 81: 34 – 46 | en_US |
dc.identifier.citedreference | Qiao J, Cohen D, Herzlinger D ( 1995 ) The metanephric blastema differentiates into collecting system and nephron epithelia in vitro. Development 121: 3207 – 3214 | en_US |
dc.identifier.citedreference | Sariola H, Saarma M ( 1999 ) GDNF and its receptors in the regulation of the ureteric branching. Int J Dev Biol 43: 413 – 418 | en_US |
dc.identifier.citedreference | Saxen L ( 1987 ) Organogenesis of the kidney. In Developmental and Cell Biology Series 19, Bard JBL, Barlow PW, Kirk DL (eds) Cambridge: Cambridge University Press | en_US |
dc.identifier.citedreference | Saxen L, Sariola H ( 1987 ) Early organogenesis of the kidney. Pediatr Nephrol 1: 385 – 392 | en_US |
dc.identifier.citedreference | Schaeren‐Wiemers N, Gerfin‐Moser A ( 1993 ) A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin‐labelled cRNA probes. Histochemistry 100: 431 – 440 | en_US |
dc.identifier.citedreference | Schuchardt A, D'Agati V, Pachnis V, Costantini F ( 1996 ) Renal agenesis and hypodysplasia in ret‐k‐ mutant mice result from defects in ureteric bud development. Development 122: 1919 – 1929 | en_US |
dc.identifier.citedreference | Shamley DR, Opperman LA, Buffenstein R, Ross FP ( 1992 ) Ontogeny of calbindin‐D28K and calbindin‐D9K in the mouse kidney, duodenum, cerebellum and placenta. Development 116: 491 – 496 | en_US |
dc.identifier.citedreference | Shawlot W, Behringer RR ( 1995 ) Requirement for Lim1 in head‐organizer function. Nature 374: 425 – 430 | en_US |
dc.identifier.citedreference | Stark K, Vainio S, Vassileva G, McMahon AP ( 1994 ) Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt‐4. Nature 372: 679 – 683 | en_US |
dc.identifier.citedreference | Torres M, Gomez‐Pardo E, Dressler GR, Gruss P ( 1995 ) Pax‐2 controls multiple steps of urogenital development. Development 121: 4057 – 4065 | en_US |
dc.identifier.citedreference | Trupp M, Arenas E, Fainzilber M, Nilsson AS, Sieber BA, Grigoriou M, Kilkenny C, Salazar‐Grueso E, Pachnis V, Arumae U ( 1996 ) Functional receptor for GDNF encoded by the c‐ret proto‐oncogene. Nature 381: 785 – 789 | en_US |
dc.identifier.citedreference | Tsang TE, Shawlot W, Kinder SJ, Kobayashi A, Kwan KM, Schughart K, Kania A, Jessell TM, Behringer RR, Tam PP ( 2000 ) Lim1 activity is required for intermediate mesoderm differentiation in the mouse embryo. Dev Biol 223: 77 – 90 | en_US |
dc.identifier.citedreference | Vainio S, Lin Y ( 2002 ) Coordinating early kidney development: lessons from gene targeting. Nat Rev Genet 3: 533 – 543 | en_US |
dc.identifier.citedreference | Vainio SJ, Uusitalo MS ( 2000 ) A road to kidney tubules via the Wnt pathway. Pediatr Nephrol 15: 151 – 156 | en_US |
dc.identifier.citedreference | Vega QC, Worby CA, Lechner MS, Dixon JE, Dressler GR ( 1996 ) Glial cell line‐derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis. Proc Natl Acad Sci USA 93: 10657 – 10661 | en_US |
dc.identifier.citedreference | Vize PD, Woolf AS, Bard JBL ( 2003 ) The Kidney, from Normal Development to Congenital Disease. London: Academic Press | en_US |
dc.identifier.citedreference | Wilkinson DG ( 1995 ) RNA detection using non‐radioactive in situ hybridization. Curr Opin Biotechnol 6: 20 – 23 | en_US |
dc.identifier.citedreference | Xu PX, Adams J, Peters H, Brown MC, Heaney S, Maas R ( 1999 ) Eya1‐deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nat Genet 23: 113 – 117 | en_US |
dc.identifier.citedreference | Xu PX, Zheng W, Huang L, Maire P, Laclef C, Silvius D ( 2003 ) Six1 is required for the early organogenesis of mammalian kidney. Development 130: 3085 – 3094 | en_US |
dc.identifier.citedreference | Yoshino K, Rubin JS, Higinbotham KG, Uren A, Anest V, Plisov SY, Perantoni AO ( 2001 ) Secreted Frizzled‐related proteins can regulate metanephric development. Mech Dev 102: 45 – 55 | en_US |
dc.identifier.citedreference | Yu J, McMahon AP, Valerius MT ( 2004 ) Recent genetic studies of mouse kidney development. Curr Opin Genet Dev 14: 550 – 557 | en_US |
dc.identifier.citedreference | Armstrong JF, Pritchard‐Jones K, Bickmore WA, Hastie ND, Bard JB ( 1993 ) The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo. Mech Dev 40: 85 – 97 | en_US |
dc.identifier.citedreference | Bouchard M, Souabni A, Mandler M, Neubuser A, Busslinger M ( 2002 ) Nephric lineage specification by Pax2 and Pax8. Genes Dev 16: 2958 – 2970 | en_US |
dc.identifier.citedreference | Buckler AJ, Pelletier J, Haber DA, Glaser T, Housman DE ( 1991 ) Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development. Mol Cell Biol 11: 1707 – 1712 | en_US |
dc.identifier.citedreference | Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP ( 2005 ) Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell 9: 283 – 292 | en_US |
dc.identifier.citedreference | Cho EA, Patterson LT, Brookhiser WT, Mah S, Kintner C, Dressler GR ( 1998 ) Differential expression and function of cadherin‐6 during renal epithelium development. Development 125: 803 – 812 | en_US |
dc.identifier.citedreference | Collins JF, Ghishan FK ( 1994 ) Molecular cloning, functional expression, tissue distribution, and in situ hybridization of the renal sodium phosphate (Na+/P(i)) transporter in the control and hypophosphatemic mouse. FASEB J 8: 862 – 868 | en_US |
dc.identifier.citedreference | Crossley PH, Martin GR ( 1995 ) The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121: 439 – 451 | en_US |
dc.identifier.citedreference | Donovan MJ, Natoli TA, Sainio K, Amstutz A, Jaenisch R, Sariola H, Kreidberg JA ( 1999 ) Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud. Dev Genet 24: 252 – 262 | en_US |
dc.identifier.citedreference | Dressler GR ( 2002 ) Development of the excretory system. In Mouse Development: Patterning, Morphogenesis, and Organogenesis, Rossant J, Tam PPL (eds) pp 395 – 420. San Diego, CA: Academic Press | en_US |
dc.identifier.citedreference | Dressler GR, Deutsch U, Chowdhury K, Nornes HO, Gruss P ( 1990 ) Pax2, a new murine paired‐box‐containing gene and its expression in the developing excretory system. Development 109: 787 – 795 | en_US |
dc.identifier.citedreference | Dressler GR, Douglass EC ( 1992 ) Pax‐2 is a DNA‐binding protein expressed in embryonic kidney and Wilms tumor. Proc Natl Acad Sci USA 89: 1179 – 1183 | en_US |
dc.identifier.citedreference | Dudley AT, Lyons KM, Robertson EJ ( 1995 ) A requirement for bone morphogenetic protein‐7 during development of the mammalian kidney and eye. Genes Dev 9: 2795 – 2807 | en_US |
dc.identifier.citedreference | Dudley AT, Robertson EJ ( 1997 ) Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos. Dev Dyn 208: 349 – 362 | en_US |
dc.identifier.citedreference | Durbec P, Marcos‐Gutierrez CV, Kilkenny C, Grigoriou M, Wartiowaara K, Suvanto P, Smith D, Ponder B, Costantini F, Saarma M, Sariola H, Pachnis V ( 1996 ) GDNF signalling through the Ret receptor tyrosine kinase. Nature 381: 789 – 793 | en_US |
dc.identifier.citedreference | Ekblom P, Alitalo K, Vaheri A, Timpl R, Saxen L ( 1980 ) Induction of a basement membrane glycoprotein in embryonic kidney: possible role of laminin in morphogenesis. Proc Natl Acad Sci USA 77: 485 – 489 | en_US |
dc.identifier.citedreference | Ekblom P, Klein G, Ekblom M, Sorokin L ( 1991 ) Laminin isoforms and their receptors in the developing kidney. Am J Kidney Dis 17: 603 – 605 | en_US |
dc.identifier.citedreference | Favor J, Sandulache R, Neuhauser‐Klaus A, Pretsch W, Chatterjee B, Senft E, Wurst W, Blanquet V, Grimes P, Sporle R, Schughart K ( 1996 ) The mouse Pax2(1Neu) mutation is identical to a human PAX2 mutation in a family with renal‐coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney. Proc Natl Acad Sci USA 93: 13870 – 13875 | en_US |
dc.identifier.citedreference | Fleming S, Symes CE ( 1987 ) The distribution of cytokeratin antigens in the kidney and in renal tumours. Histopathology 11: 157 – 170 | en_US |
dc.identifier.citedreference | Fujii T, Pichel JG, Taira M, Toyama R, Dawid IB, Westphal H ( 1994 ) Expression patterns of the murine LIM class homeobox gene lim1 in the developing brain and excretory system. Dev Dyn 199: 73 – 83 | en_US |
dc.identifier.citedreference | Gamba G, Miyanoshita A, Lombardi M, Lytton J, Lee WS, Hediger MA, Hebert SC ( 1994 ) Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium–(potassium)–chloride cotransporter family expressed in kidney. J Biol Chem 269: 17713 – 17722 | en_US |
dc.identifier.citedreference | Gao X, Chen X, Taglienti M, Rumballe B, Little MH, Kreidberg JA ( 2005 ) Angioblast‐mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa. Development 132: 5437 – 5449 | en_US |
dc.identifier.citedreference | Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR ( 2005 ) FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development 132: 3847 – 3857 | en_US |
dc.identifier.citedreference | Grobstein C ( 1955 ) Inductive interactions in the development of the mouse metanephros. J Exp Zool 130: 319 – 340 | en_US |
dc.identifier.citedreference | Gruenwald P ( 1943 ) Stimulations of nephrogenic tissues by normal and abnormal inductors. Anat Rec 86: 321 – 335 | en_US |
dc.identifier.citedreference | Hatini V, Huh SO, Herzlinger D, Soares VC, Lai E ( 1996 ) Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF‐2. Genes Dev 10: 1467 – 1478 | en_US |
dc.identifier.citedreference | Hebert SC, Mount DB, Gamba G ( 2004 ) Molecular physiology of cation‐coupled Cl − cotransport: the SLC12 family. Pflugers Arch 447: 580 – 593 | en_US |
dc.identifier.citedreference | Hellmich HL, Kos L, Cho ES, Mahon KA, Zimmer A ( 1996 ) Embryonic expression of glial cell‐line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial–mesenchymal interactions. Mech Dev 54: 95 – 105 | en_US |
dc.identifier.citedreference | Herzlinger D, Koseki C, Mikawa T, al‐Awqati Q ( 1992 ) Metanephric mesenchyme contains multipotent stem cells whose fate is restricted after induction. Development 114: 565 – 572 | en_US |
dc.identifier.citedreference | Kalatzis V, Sahly I, El‐Amraoui A, Petit C ( 1998 ) Eya1 expression in the developing ear and kidney: towards the understanding of the pathogenesis of Branchio‐Oto‐Renal (BOR) syndrome. Dev Dyn 213: 486 – 499 | en_US |
dc.identifier.citedreference | Kispert A, Vainio S, McMahon AP ( 1998 ) Wnt‐4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development 125: 4225 – 4234 | en_US |
dc.identifier.citedreference | Kispert A, Vainio S, Shen L, Rowitch DH, McMahon AP ( 1996 ) Proteoglycans are required for maintenance of Wnt‐11 expression in the ureter tips. Development 122: 3627 – 3637 | en_US |
dc.identifier.citedreference | Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, Housman D, Jaenisch R ( 1993 ) WT‐1 is required for early kidney development. Cell 74: 679 – 691 | en_US |
dc.identifier.citedreference | Laclef C, Souil E, Demignon J, Maire P ( 2003 ) Thymus, kidney and craniofacial abnormalities in Six 1 deficient mice. Mech Dev 120: 669 – 679 | en_US |
dc.identifier.citedreference | Leimeister C, Bach A, Gessler M ( 1998 ) Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family. Mech Dev 75: 29 – 42 | en_US |
dc.identifier.citedreference | Lescher B, Haenig B, Kispert A ( 1998 ) sFRP‐2 is a target of the Wnt‐4 signaling pathway in the developing metanephric kidney. Dev Dyn 213: 440 – 451 | en_US |
dc.identifier.citedreference | Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG ( 2003 ) Eya protein phosphatase activity regulates Six1–Dach–Eya transcriptional effects in mammalian organogenesis. Nature 426: 247 – 254 | en_US |
dc.identifier.citedreference | Luo G, Hofmann C, Bronckers AL, Sohocki M, Bradley A, Karsenty G ( 1995 ) BMP‐7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev 9: 2808 – 2820 | en_US |
dc.identifier.citedreference | Lyons KM, Hogan BL, Robertson EJ ( 1995 ) Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. Mech Dev 50: 71 – 83 | en_US |
dc.identifier.citedreference | Majumdar A, Vainio S, Kispert A, McMahon J, McMahon AP ( 2003 ) Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development 130: 3175 – 3185 | en_US |
dc.identifier.citedreference | Mansouri A, Chowdhury K, Gruss P ( 1998 ) Follicular cells of the thyroid gland require Pax8 gene function. Nat Genet 19: 87 – 90 | en_US |
dc.identifier.citedreference | Miner JH, Li C ( 2000 ) Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol 217: 278 – 289 | en_US |
dc.identifier.citedreference | Moore AW, McInnes L, Kreidberg J, Hastie ND, Schedl A ( 1999 ) YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis. Development 126: 1845 – 1857 | en_US |
dc.identifier.citedreference | Moore MW, Klein RD, Farinas I, Sauer H, Armanini M, Phillips H, Reichardt LF, Ryan AM, Carver‐Moore K, Rosenthal A ( 1996 ) Renal and neuronal abnormalities in mice lacking GDNF. Nature 382: 76 – 79 | en_US |
dc.identifier.citedreference | Murer H, Forster I, Biber J ( 2004 ) The sodium phosphate cotransporter family SLC34. Pflugers Arch 447: 763 – 767 | en_US |
dc.identifier.citedreference | Nishinakamura R, Matsumoto Y, Nakao K, Nakamura K, Sato A, Copeland NG, Gilbert DJ, Jenkins NA, Scully S, Lacey DL, Katsuki M, Asashima M, Yokota T ( 2001 ) Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Development 128: 3105 – 3115 | en_US |
dc.identifier.citedreference | Nishinakamura R, Osafune K ( 2006 ) Essential roles of sall family genes in kidney development. J Physiol Sci 56: 131 – 136 | en_US |
dc.identifier.citedreference | Nishinakamura R, Takasato M ( 2005 ) Essential roles of Sall1 in kidney development. Kidney Int 68: 1948 – 1950 | en_US |
dc.identifier.citedreference | Oliver G, Wehr R, Jenkins NA, Copeland NG, Cheyette BN, Hartenstein V, Zipursky SL, Gruss P ( 1995 ) Homeobox genes and connective tissue patterning. Development 121: 693 – 705 | en_US |
dc.identifier.citedreference | Pachnis V, Mankoo B, Costantini F ( 1993 ) Expression of the c‐ret proto‐oncogene during mouse embryogenesis. Development 119: 1005 – 1017 | en_US |
dc.identifier.citedreference | Perantoni AO, Timofeeva O, Naillat F, Richman C, Pajni‐Underwood S, Wilson C, Vainio S, Dove LF, Lewandoski M ( 2005 ) Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development. Development 132: 3859 – 3871 | en_US |
dc.identifier.citedreference | Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H ( 1996 ) Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382: 73 – 76 | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.