View Item 

Show simple item record

Involvement of NMDAR2A tyrosine phosphorylation in depression‐related behaviour

dc.contributor.authorTaniguchi, Sachikoen_US
dc.contributor.authorNakazawa, Takanobuen_US
dc.contributor.authorTanimura, Asamien_US
dc.contributor.authorKiyama, Yujien_US
dc.contributor.authorTezuka, Tohruen_US
dc.contributor.authorWatabe, Ayako Men_US
dc.contributor.authorKatayama, Norikazuen_US
dc.contributor.authorYokoyama, Kazumasaen_US
dc.contributor.authorInoue, Takeshien_US
dc.contributor.authorIzumi‐nakaseko, Hirokoen_US
dc.contributor.authorKakuta, Shigeruen_US
dc.contributor.authorSudo, Katsukoen_US
dc.contributor.authorIwakura, Yoichiroen_US
dc.contributor.authorUmemori, Hisashien_US
dc.contributor.authorInoue, Takafumien_US
dc.contributor.authorMurphy, Niall Pen_US
dc.contributor.authorHashimoto, Kouichien_US
dc.contributor.authorKano, Masanobuen_US
dc.contributor.authorManabe, Toshiyaen_US
dc.contributor.authorYamamoto, Tadashien_US
dc.date.accessioned2014-01-08T20:35:00Z
dc.date.available2014-01-08T20:35:00Z
dc.date.issued2009-12-02en_US
dc.identifier.citationTaniguchi, Sachiko; Nakazawa, Takanobu; Tanimura, Asami; Kiyama, Yuji; Tezuka, Tohru; Watabe, Ayako M; Katayama, Norikazu; Yokoyama, Kazumasa; Inoue, Takeshi; Izumi‐nakaseko, Hiroko ; Kakuta, Shigeru; Sudo, Katsuko; Iwakura, Yoichiro; Umemori, Hisashi; Inoue, Takafumi; Murphy, Niall P; Hashimoto, Kouichi; Kano, Masanobu; Manabe, Toshiya; Yamamoto, Tadashi (2009). "Involvement of NMDAR2A tyrosine phosphorylation in depressionâ related behaviour." The EMBO Journal 28(23): 3717-3729. <http://hdl.handle.net/2027.42/102200>en_US
dc.identifier.issn0261-4189en_US
dc.identifier.issn1460-2075en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/102200
dc.publisherJohn Wiley & Sons, Ltden_US
dc.subject.otherNMDA Receptoren_US
dc.subject.otherSrcen_US
dc.subject.otherDepression‐Related Behaviouren_US
dc.subject.otherDARPP‐32en_US
dc.subject.otherTyrosine Phosphorylationen_US
dc.titleInvolvement of NMDAR2A tyrosine phosphorylation in depression‐related behaviouren_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.identifier.pmid19834457en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102200/1/embj2009300-sup-0001.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102200/2/embj2009300.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/102200/3/embj2009300-sup-0003.pdf
dc.identifier.doi10.1038/emboj.2009.300en_US
dc.identifier.sourceThe EMBO Journalen_US
dc.identifier.citedreferenceSalter MW, Kalia LV ( 2004 ) Src kinases: a hub for NMDA receptor regulation. Nat Rev Neurosci 5: 317 – 328en_US
dc.identifier.citedreferenceHusi H, Ward MA, Choudhary JS, Blackstock WP, Grant SG ( 2000 ) Proteomic analysis of NMDA receptor‐adhesion protein signaling complex. Nat Neurosci 3: 661 – 669en_US
dc.identifier.citedreferenceIrvine EE, von Hertzen LS, Plattner F, Giese KP ( 2006 ) alphaCaMKII autophosphorylation: a fast track to memory. Trends Neurosci 29: 459 – 465en_US
dc.identifier.citedreferenceIshii T, Moriyoshi K, Sugihara H, Sakurada K, Kadotani H, Yokoi M, Akazawa C, Shigemoto R, Mizuno M, Masu M ( 1993 ) Molecular characterization of the family of the N ‐methyl‐ D ‐aspartate receptor subunits. J Biol Chem 268: 2836 – 2843en_US
dc.identifier.citedreferenceKita T, Kita H, Kitai ST ( 1984 ) Passive electrical membrane properties of rat neostriatal neurons in an in vitro slice preparation. Brain Res 300: 129 – 139en_US
dc.identifier.citedreferenceKohr G, Seeburg PH ( 1996 ) Subtype‐specific regulation of recombinant NMDA receptor‐channels by protein tyrosine kinases of the src family. J Physiol 492: 445 – 452en_US
dc.identifier.citedreferenceKornau HC, Seeburg PH, Kennedy MB ( 1997 ) Interaction of ion channels and receptors with PDZ domain proteins. Curr Opin Neurobiol 7: 368 – 373en_US
dc.identifier.citedreferenceKutsuwada T, Kashiwabuchi N, Mori H, Sakimura K, Kushiya E, Araki K, Meguro H, Masaki H, Kumanishi T, Arakawa M, Mishina M ( 1992 ) Molecular diversity of the NMDA receptor channel. Nature 358: 36 – 41en_US
dc.identifier.citedreferenceMcDonald JW, Johnston MV ( 1990 ) Physiological and pathophysiological roles of excitatory amino acids during central nervous system development. Brain Res Rev 15: 41 – 70en_US
dc.identifier.citedreferenceMiwa H, Fukaya M, Watabe AM, Watanabe M, Manabe T ( 2008 ) Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long‐term potentiation in the adult mouse CNS. J Physiol 586: 2539 – 2550en_US
dc.identifier.citedreferenceMiyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T ( 2001 ) Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor ε1 subunit. J Neurosci 21: 750 – 757en_US
dc.identifier.citedreferenceMohn AR, Gainetdinov RR, Caron MG, Koller BH ( 1999 ) Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98: 427 – 436en_US
dc.identifier.citedreferenceMonyer H, Sprengel R, Schoepfer R, Herb A, Higuchi M, Lomeli H, Burnashev N, Sakmann B, Seeburg PH ( 1992 ) Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256: 1217 – 1221en_US
dc.identifier.citedreferenceMurphy NP, Maidment NT ( 1999 ) Orphanin FQ/nociceptin modulation of mesolimbic dopamine transmission determined by microdialysis. J Neurochem 73: 179 – 186en_US
dc.identifier.citedreferenceNakazawa T, Komai S, Tezuka T, Hisatsune C, Umemori H, Semba K, Mishina M, Manabe T, Yamamoto T ( 2001 ) Characterization of Fyn‐mediated tyrosine phosphorylation sites on GluRε2 (NR2B) subunit of the N ‐methyl‐ D ‐aspartate receptor. J Biol Chem 276: 693 – 699en_US
dc.identifier.citedreferenceNakazawa T, Komai S, Watabe AM, Kiyama Y, Fukaya M, Arima‐Yoshida F, Horai R, Sudo K, Ebine K, Delawary M, Goto J, Umemori H, Tezuka T, Iwakura Y, Watanabe M, Yamamoto T, Manabe T ( 2006 ) NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity. EMBO J 25: 2867 – 2877en_US
dc.identifier.citedreferenceNarushima M, Hashimoto K, Kano M ( 2006 ) Endocannabinoid‐mediated short‐term suppression of excitatory synaptic transmission to medium spiny neurons in the striatum. Neurosci Res 54: 159 – 164en_US
dc.identifier.citedreferenceNishi A, Watanabe Y, Higashi H, Tanaka M, Nairn AC, Greengard P ( 2005 ) Glutamate regulation of DARPP‐32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades. Proc Natl Acad Sci USA 102: 1199 – 1204en_US
dc.identifier.citedreferenceOkabe S ( 2007 ) Molecular anatomy of the postsynaptic density. Mol Cell Neurosci 34: 503 – 518en_US
dc.identifier.citedreferenceOrrego F, Villanueva S ( 1993 ) The chemical nature of the main central excitatory transmitter: a critical appraisal based upon release studies and synaptic vesicle localization. Neuroscience 56: 539 – 555en_US
dc.identifier.citedreferencePetit‐Demouliere B, Chenu F, Bourin M ( 2005 ) Forced swimming test in mice: a review of antidepressant activity. Psychopharmacology 177: 245 – 255en_US
dc.identifier.citedreferenceSanacora G, Zarate CA, Krystal JH, Manji HK ( 2008 ) Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Disc 7: 426 – 437en_US
dc.identifier.citedreferenceSakai K, Miyazaki J ( 1997 ) A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. Biochem Biophys Res Commun 237: 318 – 324en_US
dc.identifier.citedreferenceScannevin RH, Huganir RL ( 2000 ) Postsynaptic organization and regulation of excitatory synapses. Nat Rev Neurosci 1: 133 – 141en_US
dc.identifier.citedreferenceSheng M, Kim MJ ( 2002 ) Postsynaptic signaling and plasticity mechanisms. Science 298: 776 – 780en_US
dc.identifier.citedreferenceSvenningsson P, Nishi A, Fisone G, Girault JA, Nairn AC, Greengard P ( 2004 ) DARPP‐32: an integrator of neurotransmission. Annu Rev Pharmacol Toxicol 44: 269 – 296en_US
dc.identifier.citedreferenceSvenningsson P, Tzavara ET, Witkin JM, Fienberg AA, Nomikos GG, Greengard P ( 2002 ) Involvement of striatal and extrastriatal DARPP‐32 in biochemical and behavioral effects of fluoxetine (Prozac). Proc Natl Acad Sci USA 99: 3182 – 3187en_US
dc.identifier.citedreferenceTezuka T, Umemori H, Akiyama T, Nakanishi S, Yamamoto T ( 1999 ) PSD‐95 promotes Fyn‐mediated tyrosine phosphorylation of the N ‐methyl‐ D ‐aspartate receptor subunit NR2A. Proc Natl Acad Sci USA 96: 435 – 440en_US
dc.identifier.citedreferenceTrullas R, Skolnick P ( 1990 ) Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. Eur J Pharmacol 185: 1 – 10en_US
dc.identifier.citedreferenceValjent E, Pascoli V, Svenningsson P, Paul S, Enslen H, Corvol JC, Stipanovich A, Caboche J, Lombroso PJ, Nairn AC, Greengard P ( 2005 ) Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum. Proc Natl Acad Sci USA 102: 491 – 496en_US
dc.identifier.citedreferenceWang YT, Salter MW ( 1994 ) Regulation of NMDA receptors by tyrosine kinases and phosphatases. Nature 369: 233 – 235en_US
dc.identifier.citedreferenceXia Z, Storm DR ( 2005 ) The role of calmodulin as a signal integrator for synaptic plasticity. Nat Rev Neurosci 6: 267 – 276en_US
dc.identifier.citedreferenceYang M, Leonard JP ( 2001 ) Identification of mouse NMDA receptor subunit NR2A C‐terminal tyrosine sites phosphorylated by coexpression with v‐Src. J Neurochem 77: 580 – 588en_US
dc.identifier.citedreferenceYokoyama K, Su I‐h, Tezuka T, Yasuda T, Mikoshiba K, Tarakhovsky A, Yamamoto T ( 2002 ) BANK regulates BCR‐induced calcium mobilization by promoting tyrosine phosphorylation of IP 3 receptor. EMBO J 21: 83 – 92en_US
dc.identifier.citedreferenceYu XM, Askalan R, Keil GJ, Salter MW ( 1997 ) NMDA receptor channel regulation by channel‐associated protein tyrosine kinase Src. Science 275: 674 – 678en_US
dc.identifier.citedreferenceZarate Jr CA, Singh J, Manji HK ( 2006 ) Cellular plasticity cascades: targets for the development of novel therapeutics for bipolar disorder. Biol Psychiatry 59: 1006 – 1020en_US
dc.identifier.citedreferenceZheng F, Gingrich MB, Traynelis SF, Conn PJ ( 1998 ) Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition. Nat Neurosci 1: 185 – 191en_US
dc.identifier.citedreferenceBelozertseva IV, Kos T, Popik P, Danysz W, Bespalov AY ( 2007 ) Antidepressant‐like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests. Eur Neuropsychopharmacol 17: 172 – 179en_US
dc.identifier.citedreferenceBoyce‐Rustay JM, Holmes A ( 2006 ) Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic‐ and antidepressant‐like effects in mice. Neuropsychopharmacology 31: 2405 – 2414en_US
dc.identifier.citedreferenceChen BS, Roche KW ( 2007 ) Regulation of NMDA receptors by phosphorylation. Neuropharmacology 53: 362 – 368en_US
dc.identifier.citedreferenceChoi DW ( 1988 ) Calcium‐mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trend Neurosci 11: 465 – 469en_US
dc.identifier.citedreferenceCollingridge GL, Bliss TVP ( 1995 ) Memories of NMDA receptors and LTP. Trend Neurosci 18: 54 – 56en_US
dc.identifier.citedreferenceCryan JF, Mombereau C ( 2004 ) In search of a depressed mouse: utility of models for studying depression‐related behavior in genetically modified mice. Mol Psychiatry 9: 326 – 357en_US
dc.identifier.citedreferenceCryan JF, Mombereau C, Vassout A ( 2005 ) The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci Biobehav Rev 29: 571 – 625en_US
dc.identifier.citedreferenceCrawley JN ( 2007 ) in What's wrong with my mice? Behavioral phenotyping of transgenic and knockout mice, 2nd edition. Wiley‐Liss: New Yorken_US
dc.identifier.citedreferenceCull‐Candy S, Brickley S, Farrant M ( 2001 ) NMDA receptor subunits: diversity, development and disease. Curr Opin Neurobiol 11: 327 – 335en_US
dc.identifier.citedreferenceEnz A, Shapiro G, Chappuis A, Dattler A ( 1994 ) Nonradioactive assay for protein phosphatase 2B (calcineurin) activity using a partial sequence of the subunit of cAMP‐dependent kinase as substrate. Anal Biochem 216: 147 – 153en_US
dc.identifier.citedreferenceHeidinger V, Manzerra P, Wang XQ, Strasser U, Yu SP, Choi DW, Behrens MM ( 2002 ) Metabotropic glutamate receptor 1‐induced upregulation of NMDA receptor current: mediation through the Pyk2/Src‐family kinase pathway in cortical neurons. J Neurosci 22: 5452 – 5461en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
embj2009300-sup-0001.pdf
Size:
1004.KB
Format:
PDF
View/Open
Name:
embj2009300.pdf
Size:
1.832MB
Format:
PDF
View/Open
Name:
embj2009300-sup-0003.pdf
Size:
455.0KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.