Examining Sexual Dysfunction in Non‐Muscle‐Invasive Bladder Cancer: Results of Cross‐Sectional Mixed‐Methods Research
dc.contributor.author | Kowalkowski, Marc A. | en_US |
dc.contributor.author | Chandrashekar, Aravind | en_US |
dc.contributor.author | Amiel, Gilad E. | en_US |
dc.contributor.author | Lerner, Seth P. | en_US |
dc.contributor.author | Wittmann, Daniela A. | en_US |
dc.contributor.author | Latini, David M. | en_US |
dc.contributor.author | Goltz, Heather Honoré | en_US |
dc.date.accessioned | 2014-09-03T16:51:39Z | |
dc.date.available | WITHHELD_12_MONTHS | en_US |
dc.date.available | 2014-09-03T16:51:39Z | |
dc.date.issued | 2014-08 | en_US |
dc.identifier.citation | Kowalkowski, Marc A.; Chandrashekar, Aravind; Amiel, Gilad E.; Lerner, Seth P.; Wittmann, Daniela A.; Latini, David M.; Goltz, Heather Honoré (2014). "Examining Sexual Dysfunction in Nonâ Muscleâ Invasive Bladder Cancer: Results of Crossâ Sectional Mixedâ Methods Research." Sexual Medicine (3): 141-151. | en_US |
dc.identifier.issn | 2050-1161 | en_US |
dc.identifier.issn | 2050-1161 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/108295 | |
dc.description.abstract | Introduction More than 70,000 new cases of bladder cancer are diagnosed in the U nited S tates annually; with 75% being non‐muscle‐invasive ( NMIBC ). Research examining sexual dysfunction in bladder cancer survivors is limited, and previous studies have focused on cystectomy patients. Aims To evaluate the impact of sexual dysfunction on NMIBC survivors. Methods Mixed‐methods data collection integrated a quantitative survey ( S tudy 1; n = 117) and semi‐structured qualitative interviews ( S tudy 2; n = 26) from a non‐overlapping sample of NMIBC survivors. We performed descriptive and classification and regression tree ( CART ) analyses of survey data and qualitative analysis of interviews. Main Outcome Measures Self‐reported sexual activity, interest in sex, and physiologic symptoms (e.g., male erectile/ejaculatory difficulties, female vaginal dryness) over the previous 4 weeks; partner communication about sexuality; contamination concerns; illness intrusiveness. Results Participants in these studies averaged 65 years of age (mean and median) and were male (77%), white (91%), and married (75%). Survey ( S tudy 1) results linked NMIBC treatment to sexual symptoms and relationship issues. Many participants reported sexual inactivity (38.8%). Sexually active participants reported erectile difficulties (60.0%), vaginal dryness (62.5%), and worry about contaminating partner with treatment agents (23.2%). While almost one‐half reported the usefulness of talking with partners about sexual function, only one‐fifth of participants reported sharing all concerns with their partners. CART analysis supported the importance of communication. One‐half of interviewees ( S tudy 2) reported sexual dysfunction. Two‐thirds reported negative impacts on their relationships, including perceived loss of intimacy and divorce; over one‐third were sexually inactive for fear of contaminating their partner or spreading NMIBC . Conclusions Survivors' sexual symptoms may result from NMIBC , comorbidities, or both. These results inform literature and practice by raising awareness about the frequency of symptoms and the impact on NMIBC survivors' intimate relationships. Further work is needed to design symptom management education programs to dispel misinformation about contamination post‐treatment and improve quality of life. Kowalkowski MA, Chandrashekar A, Amiel GE, Lerner SP, Wittmann DA, Latini DM, and Goltz HH. Examining sexual dysfunction in non‐muscle‐invasive bladder cancer: Results of cross‐sectional mixed‐methods research. Sex Med 2014;2:141–151. | en_US |
dc.publisher | National Computer Systems | en_US |
dc.publisher | Wiley Periodicals, Inc. | en_US |
dc.subject.other | Partner Communication | en_US |
dc.subject.other | Urinary Bladder Cancer | en_US |
dc.subject.other | Sexual Dysfunction | en_US |
dc.subject.other | Calmette‐Guerin Bacillus | en_US |
dc.subject.other | Cancer Survivorship | en_US |
dc.title | Examining Sexual Dysfunction in Non‐Muscle‐Invasive Bladder Cancer: Results of Cross‐Sectional Mixed‐Methods Research | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Urology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/108295/1/sm224.pdf | |
dc.identifier.doi | 10.1002/sm2.24 | en_US |
dc.identifier.source | Sexual Medicine | en_US |
dc.identifier.citedreference | Siegel R, Naishadham D, Jemal A. Cancer statistics. CA Cancer J Clin 2012; 62: 10 – 29. | en_US |
dc.identifier.citedreference | Gray RE, Fitch MI, Philips C, Labrecque M, Fergus KD, Klotz L. Prostate cancer and erectile dysfunction: Men's experiences. Int J Men's Health 2002; 1: 15 – 29. | en_US |
dc.identifier.citedreference | Schover LR, Fouladi RT, Warneke CL, Neese L, Klein EA, Zippe C, Kupelian PA. The use of treatments for erectile dysfunction among survivors of prostate carcinoma. Cancer 2002; 95: 2397 – 2407. | en_US |
dc.identifier.citedreference | Koya MP, Simon MA, Soloway MS. Complications of intravesical therapy for urothelial cancer of the bladder. J Urol 2006; 175: 2004 – 2010. | en_US |
dc.identifier.citedreference | Sexton WJ, Wiegand LR, Correa JJ, Politis C, Dickinson SI, Kang LC. Bladder cancer: A review of non‐muscle invasive disease. Cancer Control 2010; 17: 256 – 268. | en_US |
dc.identifier.citedreference | Allareddy V, Kennedy J, West MM, Konety BR. Quality of life in long‐term survivors of bladder cancer. Cancer 2006; 106: 2355 – 2362. | en_US |
dc.identifier.citedreference | Melisko ME, Goldman M, Rugo HS. Amelioration of sexual adverse effects in the early breast cancer patient. J Cancer Surviv 2010; 4: 247 – 255. | en_US |
dc.identifier.citedreference | Zippe CD, Raina R, Shah AD, Massanyi EZ, Agarwal A, Ulchaker J, Jones S, Klein E. Female sexual dysfunction after radical cystectomy: A new outcome measure. Urology 2004; 63: 1153 – 1157. | en_US |
dc.identifier.citedreference | Wittmann D, Foley S, Balon R. A biopsychosocial approach to sexual recovery after prostate cancer surgery: The role of grief and mourning. J Sex Marital Ther 2011; 37: 130 – 144. | en_US |
dc.identifier.citedreference | Lindau ST, Schumm LP, Laumann EO, Levinson W, O'Muircheartaigh CA, Waite LJ. A study of sexuality and health among older adults in the United States. N Engl J Med 2007; 357: 762 – 774. | en_US |
dc.identifier.citedreference | Flynn KE, Jeffery DD, Keefe FJ, Porter LS, Shelby RA, Fawzy MR, Gosselin TK, Reeve BB, Weinfurt KP. Sexual functioning along the cancer continuum: Focus group results from the Patient‐Reported Outcomes Measurement Information System (PROMIS(R). Psychooncology 2011; 20: 378 – 386. | en_US |
dc.identifier.citedreference | van der Aa MN, Bekker MD, van der Kwast TH, Essink‐Bot ML, Steyerberg EW, Zwarthoff EC, Sen FE, Elzevier HW. Sexual function of patients under surveillance for bladder cancer. BJU Int 2009; 104: 35 – 40. | en_US |
dc.identifier.citedreference | Laumann EO, Waite LJ. Sexual dysfunction among older adults: Prevalence and risk factors from a nationally representative U.S. probability sample of men and women 57–85 years of age. J Sex Med 2008; 5: 2300 – 2311. | en_US |
dc.identifier.citedreference | Porter LS, Keefe FJ, Hurwitz H, Faber M. Disclosure between patients with gastrointestinal cancer and their spouses. Psychooncology 2005; 14: 1030 – 1042. | en_US |
dc.identifier.citedreference | Derogatis LR. BSI‐18: Administration, scoring and procedures manual. Minneapolis, MN: National Computer Systems; 2000. | en_US |
dc.identifier.citedreference | Devins GM. Illness intrusiveness and the psychosocial impact of lifestyle disruptions in chronic life‐threatening disease. Adv Ren Replace Ther 1994; 1: 251 – 263. | en_US |
dc.identifier.citedreference | Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC, Kaasa S, Klee M, Osoba D, Razavi D, Rofe P, Schraub S, Sneeuw K, Sullivan M, Takeda F. The European Organization for Research and Treatment of Cancer QLQ‐C30: A quality‐of‐life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993; 85: 365 – 376. | en_US |
dc.identifier.citedreference | Bokhour BG, Clark JA, Inui TS, Silliman RA, Talcott JA. Sexuality after treatment for early prostate cancer: Exploring the meanings of “erectile dysfunction”. J Gen Intern Med 2001; 16: 649 – 655. | en_US |
dc.identifier.citedreference | Laumann EO, Paik A, Rosen RC. Sexual dysfunction in the United States: Prevalence and predictors. JAMA 1999; 281: 537 – 544. | en_US |
dc.identifier.citedreference | Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study. J Urol 1994; 151: 54 – 61. | en_US |
dc.identifier.citedreference | Mohamed NE, Diefenbach MA, Goltz HH, Lee CT, Latini D, Kowalkowski M, Philips C, Hassan W, Hall SJ. Muscle invasive bladder cancer: From diagnosis to survivorship. Adv Urol 2012; 2012: 142135. | en_US |
dc.identifier.citedreference | Stav K, Leibovici D, Goren E, Livshitz A, Siegel YI, Lindner A, Zisman A. Adverse effects of cystoscopy and its impact on patients' quality of life and sexual performance. Isr Med Assoc J 2004; 6: 474 – 478. | en_US |
dc.identifier.citedreference | Sighinolfi MC, Micali S, De Stefani S, Mofferdin A, Ferrari N, Giacometti M, Bianchi G. Bacille Calmette‐Guerin intravesical instillation and erectile function: Is there a concern? Andrologia 2007; 39: 51 – 54. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.