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Thyroid control over biomembranes. II. Rat liver nuclei

dc.contributor.authorShaw, Michael J.en_US
dc.contributor.authorHoch, Frederic L.en_US
dc.date.accessioned2006-04-07T16:25:04Z
dc.date.available2006-04-07T16:25:04Z
dc.date.issued1976-11-01en_US
dc.identifier.citationShaw, Michael J., Hoch, Frederic L. (1976/11/01)."Thyroid control over biomembranes. II. Rat liver nuclei." Life Sciences 19(9): 1359-1364. <http://hdl.handle.net/2027.42/21650>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T99-479DRXK-14F/2/9ca0a3819b9a763c55b411a2dcf3b811en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/21650
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=186684&dopt=citationen_US
dc.description.abstractLiver cell nuclei obtained from hypothyroid rats contain phospholipids in which the relative amounts of unsaturated fatty acids differ from those in normal nuclei: linoleic (18:2) and docosatrienoic (20:3) increase, [gamma]-linolenic (18:3 [omega]6) appears, and arachidonic acid (20:4) decreases. The unsaturation index decreases by 7%, the ratio 20:4/18:2 by 63%. These changes resemble the pattern reported for the liver mitochondrial inner membrane, and are evidence for a defect in [Delta]5-desaturation in the livers of hypothyroid rats. The membrane-dependency of the activity of the nucclear glucose-6-phosphate phosphohydrolase is slightly but consistently different in hypothyroids and normals.en_US
dc.format.extent319917 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleThyroid control over biomembranes. II. Rat liver nucleien_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Internal Medicine and Biological Chemistry The University of Michigan Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartments of Internal Medicine and Biological Chemistry The University of Michigan Medical Center, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid186684en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/21650/1/0000034.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0024-3205(76)90434-3en_US
dc.identifier.sourceLife Sciencesen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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