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Loss of glucocorticoid regulation of plasminogen activator activity in anucleate rat hepatoma cells

dc.contributor.authorBarouski, P. A.en_US
dc.contributor.authorGelehrter, Thomas D.en_US
dc.date.accessioned2006-04-07T17:20:45Z
dc.date.available2006-04-07T17:20:45Z
dc.date.issued1980-10-31en_US
dc.identifier.citationBarouski, P. A., Gelehrter, T. D. (1980/10/31)."Loss of glucocorticoid regulation of plasminogen activator activity in anucleate rat hepatoma cells." Biochemical and Biophysical Research Communications 96(4): 1540-1546. <http://hdl.handle.net/2027.42/23118>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4DMXFR4-2CF/2/50a50b69ede43e25f2bcf6cbadb5853aen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/23118
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7192557&dopt=citationen_US
dc.description.abstractGlucocorticoids decrease the plasminogen activator activity of rat hepatoma cells through production of an inhibitor. We have examined the dexamethasone regulation of plasminogen activator in anucleate rat hepatoma cells to investigate the role of the nucleus in the steroid regulation of this membrane-associated phenomenon. Dexamethasone did not affect either the intra- or extra-cellular plasminogen activator activity of the anucleate cells, and did not induce production of an inhibitor of plasminogen activator. Therefore, glucocorticoid regulation of plasminogen activator activity requires the presence of an intact nucleus.en_US
dc.format.extent394500 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleLoss of glucocorticoid regulation of plasminogen activator activity in anucleate rat hepatoma cellsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics and Internal Medicine University of Michigan Medical School, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics and Internal Medicine University of Michigan Medical School, Ann Arbor, MI 48109, USAen_US
dc.identifier.pmid7192557en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/23118/1/0000041.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(80)91349-2en_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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