View Item 

Show simple item record

Visualization of opiate receptors and opioid peptides in sequential brain sections

dc.contributor.authorLewis, Michael E.en_US
dc.contributor.authorKhachaturian, Henryen_US
dc.contributor.authorWatson, Stanley J.en_US
dc.date.accessioned2006-04-07T17:49:01Z
dc.date.available2006-04-07T17:49:01Z
dc.date.issued1982-09en_US
dc.identifier.citationLewis, Michael E., Khachaturian, Henry, Watson, Stanley J. (1982/09)."Visualization of opiate receptors and opioid peptides in sequential brain sections." Life Sciences 31(12-13): 1347-1350. <http://hdl.handle.net/2027.42/23888>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T99-47CMW11-30/2/2e5359e99b594d9aab717b5eee758192en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/23888
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6292628&dopt=citationen_US
dc.description.abstractAutoradiographic and immunocytochemical studies were carried out on adjacent sections from formaldehyde-perfused rat brains in order to directly correlate the distribution of opiate receptors and opioid peptides. Perfusion fixation of the brains resulted in a partial loss of specific [3H]naloxone binding with essentially no change in the pharmacological properties of the remaining sites. When the distribution of sites was compared to that of enkaphalin immunoreactivity in adjacent sections, striking correlations were observed in a number of areas throughout the neuraxis. Adjacent section autoradiography-immunocytochemistry should provide a useful tool for relating the anatomical distribution of opiate receptor subtypes to different opioid peptide neuronal systems.en_US
dc.format.extent392827 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleVisualization of opiate receptors and opioid peptides in sequential brain sectionsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumMental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumMental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumMental Health Research Institute University of Michigan, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid6292628en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/23888/1/0000127.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0024-3205(82)90378-2en_US
dc.identifier.sourceLife Sciencesen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
0000127.pdf
Size:
383.6KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.