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Responses of normal and malignant cells to collagen, collagen-derived peptides and the C5-related tumor cell chemotactic peptide

dc.contributor.authorWass, John A.en_US
dc.contributor.authorVarani, Jamesen_US
dc.contributor.authorPiontek, Gerald E.en_US
dc.contributor.authorWard, Peter A.en_US
dc.contributor.authorOrr, F. Williamen_US
dc.date.accessioned2006-04-07T17:59:16Z
dc.date.available2006-04-07T17:59:16Z
dc.date.issued1981-12en_US
dc.identifier.citationWass, John A., Varani, James, Piontek, Gerald E., Ward, Peter A., Orr, F. William (1981/12)."Responses of normal and malignant cells to collagen, collagen-derived peptides and the C5-related tumor cell chemotactic peptide." Cell Differentiation 10(6): 329-332. <http://hdl.handle.net/2027.42/24181>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B73GV-47PGYGB-7Y/2/53414a36b39c639399fa44d34b2170caen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/24181
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7317948&dopt=citationen_US
dc.description.abstractTwo variant subpopulations of murine fibrosarcoma cells that differ significantly in their malignant potential and normal mouse fibroblasts were compared with regard to ability to respond chemotactically to collagen, collagen-derived peptides and the C5-derived tumor cell chemotactic peptide. Two distinct patterns of responsiveness were observed. The normal fibroblasts and non-metastasizing fibrosarcoma cells responded to the collagen products but not the C5 peptide. The metastasizing fibrosarcoma cells responded to the C5 peptide but not to the collagen products. These findings emphasize the similarities between the normal fibroblasts and the non-metastasizing fibrosarcoma cells.en_US
dc.format.extent281496 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleResponses of normal and malignant cells to collagen, collagen-derived peptides and the C5-related tumor cell chemotactic peptideen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationotherDepartment of Pathology, University of Manitoba Medical School, Winnipeg, Manitoba, Canadaen_US
dc.identifier.pmid7317948en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/24181/1/0000440.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0045-6039(81)90024-5en_US
dc.identifier.sourceCell Differentiationen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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