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| Title: | 111In-8-hydroxyquinoline platelet labeling in dogs |
| Author(s): | Porter-Fink, Vicki L.
Eckhauser, Frederic E. |
| Issue Date: | Jul-1981 |
| Publisher: | Elsevier |
| Citation: | Porter-Fink, V. L., Eckhauser, Frederic E. (1981/07)."111In-8-hydroxyquinoline platelet labeling in dogs." Journal of Surgical Research 31(1): 87-92. <http://hdl.handle.net/2027.42/24318> |
| Abstract: | This report validates a technique of separating and labeling canine platelets using indium-111-labeled 8-hydroxyquinoline (111In-8-HQ). Platelet survival time in six normal dogs was 6.3 +/- 0.7 (SD) days. Labeling efficiency using this technique was 51.8 +/- 9.2% (SEM) and elution loss of 111In-8-HQ label from platelets was consistently less than 4%. 111In label offers no observable advantages over the more traditional 51Cr label for platelet survival studies. However, the high efficiency labeling and -[gamma]-emission characteristics of 111In-8-HQ make it more suitable for non-invasive clot localization in patients with early pulmonary emboli and peripheral venous thrombi. |
| Persistent URL (URI): | http://hdl.handle.net/2027.42/24318
http://www.sciencedirect.com/science/article/B6WM6-4BNF4HK-2
TG/2/e0fa1bdbc40eb0eecfb139fc9614e893
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db
=pubmed&list_uids=6789007&dopt=citation |
| Other Identifiers: | 10.1016/0022-4804(81)90034-2 |
| PMID: | 6789007 |
| Appears in Collections: | Interdisciplinary and Peer-Reviewed
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| 0000585.pdf | | 463Kb | Adobe PDF | View/Open |
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