GABA and benzodiazepine receptors in basal ganglia function

Young, Anne B.; Pan, Helen S.; Ciliax, Brian J.; Penney, John B.

1984-06-29

Citation: Young, Anne B., Pan, Helen S., Ciliax, Brian J., Penney, John B. (1984/06/29)."GABA and benzodiazepine receptors in basal ganglia function." Neuroscience Letters 47(3): 361-367. <http://hdl.handle.net/2027.42/24774>

Abstract: GABA and its associated benzodiazepine interactions play an important role in basal ganglia function. Distinctive GABA, benzodiazepine and opiate receptor changes occur in response to striatal lesions and in the human neurodegenerative disorder, Huntington's disease (HD). In animal experiments, the in vivo administration of [3H]flunitrazepam labels benzodiazepine receptors and can demonstrate the receptor changes seen after striatal lesions. It should be possible to measure these receptors in vivo in humans using positron-emission tomographic scanning.

DOIs: http://dx.doi.org/10.1016/0304-3940(84)90540-8

PMID: 6089057

URI: http://www.sciencedirect.com/science/article/B6T0G-482RJ1R-1N/2/b4b45fc1597ea919563de07783668fdd
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6089057&dopt=citation

Handle: http://hdl.handle.net/2027.42/24774

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