Hyperosmotic arabinose solutions open the tight junctions between brain capillary endothelial cells in tissue culture

Dorovini-Zis, Katerina; Bowman, Phillip D.; Lorris Betz, A.; Goldstein, Gary W.

1984-06-08

Citation: Dorovini-Zis, Katerina, Bowman, Phillip D., Lorris Betz, A., Goldstein, Gary W. (1984/06/08)."Hyperosmotic arabinose solutions open the tight junctions between brain capillary endothelial cells in tissue culture." Brain Research 302(2): 383-386. <http://hdl.handle.net/2027.42/24782>

Abstract: Tight junctions between bovine brain capillary endothelial cells in primary cell culture are impermeable to horseradish peroxidase (HRP) after 5 min of incubation. However, following 1-5 min of exposure to 1.6 M arabinose, HRP penetrates the extracellular space between successive tight junctions. Endothelial cells in control cultures contain a small number of cytoplasmic pits and vesicles containing HRP which do not increase in number after hyperosmotic treatment.

DOIs: http://dx.doi.org/10.1016/0006-8993(84)90254-3

PMID: 6733518

URI: http://www.sciencedirect.com/science/article/B6SYR-4835WV8-DH/2/86c92e418ef05d37ffac4583271d22ea
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6733518&dopt=citation

Handle: http://hdl.handle.net/2027.42/24782

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