Radiotherapeutic alternatives to standard management of adenocarcinoma of the endometrium
dc.contributor.author | Andersen, Willie A. | en_US |
dc.contributor.author | Peters, III, William A. | en_US |
dc.contributor.author | Fechner, Robert E. | en_US |
dc.contributor.author | Morley, George W. | en_US |
dc.contributor.author | Thornton, Jr. , W. Norman | en_US |
dc.date.accessioned | 2006-04-07T18:36:24Z | |
dc.date.available | 2006-04-07T18:36:24Z | |
dc.date.issued | 1983-12 | en_US |
dc.identifier.citation | Andersen, Willie A., Peters, III, William A., Fechner, Robert E., Morley, George W., Thornton, Jr., W. Norman (1983/12)."Radiotherapeutic alternatives to standard management of adenocarcinoma of the endometrium." Gynecologic Oncology 16(3): 383-392. <http://hdl.handle.net/2027.42/25049> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WG6-4C52KXF-FG/2/a85a5352b5a76d3d58c82714b7512c66 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25049 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6418622&dopt=citation | en_US |
dc.description.abstract | Primary radiotherapy as an alternative management for adenocarcinoma of the endometrium was chosen for 117 patients treated at the University of Michigan Medical Center and University of Virginia Medical Center. Cases were selected for radiation because of contraindications to surgery (52.2%) or by protocol for disease outside the endometrium (47.8%). An overall 5-year actuarial survival rate of 49.6% was attained for all stages, with 55% 5-year survival for disease limited to the uterus or cervix. Stage and grade were the most significant risk factors. The addition of external-beam irradiation did not improve local failure rates or survival. Heyman's uterine packing technique was slightly more successful than uterine "line sources" in controlling local disease (P = 0.08). Treatment-related mortality (0.8%) and morbidity (6.8%) were minimal. Surgery, whenever possible, remains the "best standard therapy" but the radiotherapeutic alternative is of significant benefit for those deemed nonsurgical candidates. | en_US |
dc.format.extent | 733980 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Radiotherapeutic alternatives to standard management of adenocarcinoma of the endometrium | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Otolaryngology | en_US |
dc.subject.hlbsecondlevel | Ophthalmology | en_US |
dc.subject.hlbsecondlevel | Oncology and Hematology | en_US |
dc.subject.hlbsecondlevel | Obstetrics and Gynecology | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Department of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationother | Department of Obstetrics and Gynecology University of Virginia Medical Center, P. O. Box 465, Charlottesville, Virginia 22908, USA | en_US |
dc.contributor.affiliationother | Department of Pathology, University of Virginia Medical Center, P. O. Box 465, Charlottesville, Virginia 22908, USA | en_US |
dc.contributor.affiliationother | Department of Obstetrics and Gynecology University of Virginia Medical Center, P. O. Box 465, Charlottesville, Virginia 22908, USA | en_US |
dc.identifier.pmid | 6418622 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25049/1/0000477.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0090-8258(83)90166-X | en_US |
dc.identifier.source | Gynecologic Oncology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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