Dissolution rate of apatite powders in acidic fluoride solutions and the relationship to hydroxyapatite disk and bovine enamel behavior
dc.contributor.author | Ludwig, A. | en_US |
dc.contributor.author | Dave, S. C. | en_US |
dc.contributor.author | Higuchi, William I. | en_US |
dc.contributor.author | Fox, Jeffrey L. | en_US |
dc.contributor.author | Katdare, Ashok | en_US |
dc.date.accessioned | 2006-04-07T18:39:30Z | |
dc.date.available | 2006-04-07T18:39:30Z | |
dc.date.issued | 1983-08 | en_US |
dc.identifier.citation | Ludwig, A., Dave, S. C., Higuchi, W. I., Fox, J. L., Katdare, A. (1983/08)."Dissolution rate of apatite powders in acidic fluoride solutions and the relationship to hydroxyapatite disk and bovine enamel behavior." International Journal of Pharmaceutics 16(1): 1-10. <http://hdl.handle.net/2027.42/25136> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T7W-4777MX0-60/2/40ac8798ed97b5b98de1ea7b6c44c1b0 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/25136 | |
dc.description.abstract | The dissolution kinetics of synthetic hydroxyapatite (HAP) and carbonate-containing HAP powders have been studied in fluoride-containing acetate buffer solutions partially saturated with respect to HAP (KFAP = 10-115 to 10-123). The experimental results indicate that in the case of HAP powders the dissolution rates become very slow when the KFAP values of the dissolution medium are larger than 10-119. For the carbonate-containing apatites, however, there is a significant dissolution in the region 10-115 >= KFAP >= 10-119 which is in the region of physiological and therapeutic significance.The present results with the HAP powder together with HAP pellet data show that the dissolution of HAP pellets in the region 10-114 > KFAP > 10-119 results from an extended transient period rising from sustained deposition of F- on the surface and at intermediate depths in the `lesion'. Similar effects have also been observed with bovine teeth dissolution in acidic F- solutions. | en_US |
dc.format.extent | 782766 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Dissolution rate of apatite powders in acidic fluoride solutions and the relationship to hydroxyapatite disk and bovine enamel behavior | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Ml 48109, U.S.A. | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Ml 48109, U.S.A. | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Ml 48109, U.S.A. | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Ml 48109, U.S.A. | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Ml 48109, U.S.A. | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/25136/1/0000569.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0378-5173(83)90122-9 | en_US |
dc.identifier.source | International Journal of Pharmaceutics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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