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Prostaglandin E1 and prostaglandin I2 modulation of superoxide production by human neutrophils

dc.contributor.authorFantone, Joseph C.en_US
dc.contributor.authorKinnes, D. A.en_US
dc.date.accessioned2006-04-07T18:41:22Z
dc.date.available2006-04-07T18:41:22Z
dc.date.issued1983-06-15en_US
dc.identifier.citationFantone, J. C., Kinnes, D. A. (1983/06/15)."Prostaglandin E1 and prostaglandin I2 modulation of superoxide production by human neutrophils." Biochemical and Biophysical Research Communications 113(2): 506-512. <http://hdl.handle.net/2027.42/25188>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4F03B28-11M/2/3c897f99b559d615a5c895113ee2f4caen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/25188
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6307290&dopt=citationen_US
dc.description.abstract15(S)-15-methyl-prostaglandin E1 and prostaglandin I2 rapidly and reversibly inhibit formyl-methionyl-leucyl-phenylalanine induced superoxide production by human neutrophils. In contrast, 15(S)-15-methyl-prostaglandin E1 and prostaglandin I2 did not alter the rate or the total amount of superoxide production by human neutrophils stimulated with either phorbol myristate acetate or arachidonic acid. These data suggest that the production of superoxide anion by human neutrophils may be mediated by at least two mechanisms, one regulated by prostaglandins and intracellular cyclic adenosine monophosphate levels and a second independent of prostaglandin modulation.en_US
dc.format.extent396556 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleProstaglandin E1 and prostaglandin I2 modulation of superoxide production by human neutrophilsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USAen_US
dc.identifier.pmid6307290en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/25188/1/0000627.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(83)91754-0en_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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