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Myelopathy following intrathecal chemotherapy in a patient with extensive burkitt's lymphoma and altered immune status

dc.contributor.authorBates, Susan Weilen_US
dc.contributor.authorMcKeever, Paul E.en_US
dc.contributor.authorMasur, Henryen_US
dc.contributor.authorLevens, Daviden_US
dc.contributor.authorMacher, Abeen_US
dc.contributor.authorArmstrong, Garyen_US
dc.contributor.authorMagrath, Ian T.en_US
dc.date.accessioned2006-04-07T19:07:33Z
dc.date.available2006-04-07T19:07:33Z
dc.date.issued1985-04en_US
dc.identifier.citationBates, Susan, McKeever, Paul, Masur, Henry, Levens, David, Macher, Abe, Armstrong, Gary, Magrath, Ian T. (1985/04)."Myelopathy following intrathecal chemotherapy in a patient with extensive burkitt's lymphoma and altered immune status." The American Journal of Medicine 78(4): 697-702. <http://hdl.handle.net/2027.42/25727>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6TDC-4CDRGJT-2X/2/924d29087e1cbc48d28405037aa308fben_US
dc.identifier.urihttps://hdl.handle.net/2027.42/25727
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2580436&dopt=citationen_US
dc.description.abstractA 30-year-old homosexual man presented with widespread Burkitt's lymphoma. On the basis of immunologic and viral studies, he was suspected of having the acquired Immune deficiency syndrome. Following chemotherapy that included Intrathecal cytosine arabinoside and methotrexate, brain stem edema, paraplegia, and an elevated cerebrospinal fluid level of myelin basic protein developed. Autopsy revealed vacuolar demyelination of spinal cord, brain stem, and cerebellum. The pathologic findings were similar to those reported to occur In myelopathy associated with intrathecal chemotherapy, but far more extensive. The contribution of the suspected acquired immune deficiency syndrome is unknown.en_US
dc.format.extent3551634 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleMyelopathy following intrathecal chemotherapy in a patient with extensive burkitt's lymphoma and altered immune statusen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelFamily Medicine and Primary Careen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationotherClinical Oncology Program, Division of Cancer Treatment, National Cancer Institute, the Critical Care Medicine Department, Clinical Center, Bethesda, Maryland, USA; Laboratory of Pathology, Division of Cancer Biology and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USAen_US
dc.contributor.affiliationotherFood and Drug Administration, Bureau of Biologics, Division of Virology, Bethesda, Maryland, USAen_US
dc.contributor.affiliationotherFood and Drug Administration, Bureau of Biologics, Division of Virology, Bethesda, Maryland, USAen_US
dc.contributor.affiliationotherFood and Drug Administration, Bureau of Biologics, Division of Virology, Bethesda, Maryland, USAen_US
dc.contributor.affiliationotherFood and Drug Administration, Bureau of Biologics, Division of Virology, Bethesda, Maryland, USAen_US
dc.identifier.pmid2580436en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/25727/1/0000284.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0002-9343(85)90417-6en_US
dc.identifier.sourceThe American Journal of Medicineen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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