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Elevated temperature produces cystine depletion in cystinotic fibroblasts

dc.contributor.authorLemons, Rosemary M.en_US
dc.contributor.authorPisoni, Ronald L.en_US
dc.contributor.authorChristensen, Halvor N.en_US
dc.contributor.authorThoene, Jess G.en_US
dc.date.accessioned2006-04-07T19:22:41Z
dc.date.available2006-04-07T19:22:41Z
dc.date.issued1986-12-10en_US
dc.identifier.citationLemons, Rosemary M., Pisoni, Ronald L., Christensen, Halvor N., Thoene, Jess G. (1986/12/10)."Elevated temperature produces cystine depletion in cystinotic fibroblasts." Biochimica et Biophysica Acta (BBA) - General Subjects 884(3): 429-434. <http://hdl.handle.net/2027.42/25945>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T1W-47MCPJK-178/2/0e959f2ab03187dfef6ca22f2f64c19ben_US
dc.identifier.urihttps://hdl.handle.net/2027.42/25945
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3778933&dopt=citationen_US
dc.description.abstractIncreasing the incubation temperature of cystinotic fibroblasts to 40 or 43[deg]C produces a 70-80% decrease in lysosomal cystine content within 24-48 h. This effect is probably mediated by an altered substrate affinity for another lysosomal transport protein.en_US
dc.format.extent694285 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleElevated temperature produces cystine depletion in cystinotic fibroblastsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMaterials Science and Engineeringen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Pediatrics and Biological Chemistry, The University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumDepartments of Pediatrics and Biological Chemistry, The University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumDepartments of Pediatrics and Biological Chemistry, The University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumDepartments of Pediatrics and Biological Chemistry, The University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.identifier.pmid3778933en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/25945/1/0000008.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0304-4165(86)90193-5en_US
dc.identifier.sourceBiochimica et Biophysica Actaen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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