A tail withdrawal procedure for assessing analgesic activity in rhesus monkeys
dc.contributor.author | Dykstra, Linda A. | en_US |
dc.contributor.author | Woods, James H. | en_US |
dc.date.accessioned | 2006-04-07T19:30:20Z | |
dc.date.available | 2006-04-07T19:30:20Z | |
dc.date.issued | 1986-06 | en_US |
dc.identifier.citation | Dykstra, Linda A., Woods, James H. (1986/06)."A tail withdrawal procedure for assessing analgesic activity in rhesus monkeys." Journal of Pharmacological Methods 15(3): 263-269. <http://hdl.handle.net/2027.42/26151> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B73F9-477XP6F-RT/2/4b135f69b5c3ff100f373d8361f620cb | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/26151 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3713205&dopt=citation | en_US |
dc.description.abstract | Rhesus monkeys were restrained in chairs from which their tails hung free so that their tails could be immersed into a thermos of water. Monkeys consistently kept their tails in 38-40[deg]C water for at least 20 sec, but withdrew them from 55[deg]C water in 1-4 sec. Tail withdrawal latencies from 55[deg]C water remained consistent over a period of 3 hr. Morphine produced dose-dependent increases in tail withdrawal latencies from 55[deg]C water, whereas pentobarbital, haloperidol, and phencyclidine did not increase tail withdrawal latencies except at doses that produced marked sedation. | en_US |
dc.format.extent | 408347 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | A tail withdrawal procedure for assessing analgesic activity in rhesus monkeys | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan, USA | en_US |
dc.identifier.pmid | 3713205 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/26151/1/0000228.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0160-5402(86)90056-2 | en_US |
dc.identifier.source | Journal of Pharmacological Methods | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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