1,1'-trimethylenebisthymine as synthetic model of dinucleotide TpT Electrochemical reduction
dc.contributor.author | Malinski, Tadeusz | en_US |
dc.contributor.author | Langer, Jerzy J. | en_US |
dc.contributor.author | Moiroux, Jacques | en_US |
dc.contributor.author | Elving, Philip Juliber | en_US |
dc.date.accessioned | 2006-04-07T19:31:43Z | |
dc.date.available | 2006-04-07T19:31:43Z | |
dc.date.issued | 1986-04-25 | en_US |
dc.identifier.citation | Malinski, Tadeusz, Langer, Jerzy J., Moiroux, Jacques, Elving, Philip J. (1986/04/25)."1,1'-trimethylenebisthymine as synthetic model of dinucleotide TpT Electrochemical reduction." Journal of Electroanalytical Chemistry 201(2): 329-345. <http://hdl.handle.net/2027.42/26190> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TGB-44YXMJH-DG/2/b72279694ba96d28f66881f023389a11 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/26190 | |
dc.description.abstract | The electrochemical reduction of 1,1'-trimethylenebisthymine (Thy(C3)Thy) in dimethylsulfoxide was investigated using dc polarography, cyclic voltammetry, controlled potential electrolysis and spectroelectrochemistry. Thy(C3)Thy is reduced in a two-election step (E1/2 = -2.40 V) to a diradical dianion which abstracts protons from the parent Thy(C3)Thy to form a neutral free diradical and the Thy(C3)Thy dianion. The neutral free diradical is further reduced and protonated to form 1,1'-trimethylenebisdihydrothymine. The dianion forms insoluble mercury salts producing up to three oxidation peaks (Epa between -0.35 and -0.07V). The effect of added base on the electrochemical and spectroelectrochemical behavior is described. The number of layers of the mercury- Thy(C3)Thy salt adsorbed in the anodic and stripped in the cathodic processes was calculated. The mechanism of adsorption is discussed. | en_US |
dc.format.extent | 1044318 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | 1,1'-trimethylenebisthymine as synthetic model of dinucleotide TpT Electrochemical reduction | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Materials Science and Engineering | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Chemistry, University of Michigan, Ann Arbor, MI 48109 U.S.A. | en_US |
dc.contributor.affiliationother | Department of Chemistry, Oakland University, Rochester, MI 48063 U.S.A. | en_US |
dc.contributor.affiliationother | Department of Chemistry, Oakland University, Rochester, MI 48063 U.S.A. | en_US |
dc.contributor.affiliationother | Lab. Chimie Analitique, U.A. C.N.R.S. No. 484, Fac. Pharmacie, Université Paris V, 4 Ave. Observatoire, 75270 Paris Cedex 06 France | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/26190/1/0000269.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0022-0728(86)80058-4 | en_US |
dc.identifier.source | Journal of Electroanalytical Chemistry | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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