[omega]-iodophenyl fatty acids: A convenient method of radioiodination

Otto, Charlotte A.; Lee, H.; Mangner, Thomas J.; Wieland, Donald M.

1986

Citation: Otto, C. A., Lee, H., Mangner, T. J., Wieland, D. M. (1986)."[omega]-iodophenyl fatty acids: A convenient method of radioiodination." International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes 37(3): 205-210. <http://hdl.handle.net/2027.42/26370>

Abstract: A solid-phase radioiodination technique for [omega]-iodophenyl fatty acids using ammonium sulfate is described. The radioiodinations are (1) regioselective, (2) high in yield (95%), (3) short in reaction time (1 h) and (4) capable of yielding high specific activity products although at lower yields. Purification is exceptionally simple: a single passage through an ion exchange column to remove unreacted *I- is all that is required. Syntheses of several [omega]-iodophenyl fatty acids are also described.

DOIs: http://dx.doi.org/10.1016/0883-2889(86)90172-3

PMID: 3019931

URI: http://www.sciencedirect.com/science/article/B6X3S-473123D-56/2/b67d9db68281b051dd4dde9f74286731
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3019931&dopt=citation

Handle: http://hdl.handle.net/2027.42/26370

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