Multiple depressive episodes and plasma postdexamethasone cortisol levels

Meador-Woodruff, James H.; Gurguis, George; Grunhaus, Leon; Haskett, Roger F.; Greden, John F.

1987-05

Citation: Meador-Woodruff, James H., Gurguis, George, Grunhaus, Leon, Haskett, Roger F., Greden, John F. (1987/05)."Multiple depressive episodes and plasma postdexamethasone cortisol levels." Biological Psychiatry 22(5): 583-592. <http://hdl.handle.net/2027.42/26723>

Abstract: The hypothalamic-pituitary-adrenal (HPA) axis is dysregulated in many patients with major depressive disorder (MDD). To determine whether or not a past history of depressive episodes is associated with this dysregulation, we studied the relationships among number of past depressive episodes, number of previous hospitalizations for depression, and number of years since first depressive episode and biological markers of depression (postdexamethasone plasma cortisol levels and dexamethasone suppressor/nonsuppressor status). No significant relationships were detected.

DOIs: http://dx.doi.org/10.1016/0006-3223(87)90186-7

PMID: 3580433

URI: http://www.sciencedirect.com/science/article/B6T4S-485RJYG-33/2/ac0e142e080717859f81133026a38a04
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3580433&dopt=citation

Handle: http://hdl.handle.net/2027.42/26723

Show full item record