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Two bovine genes for cytochrome c oxidase subunit IV: a processed pseudogene and an expressed gene

dc.contributor.authorBachman, Nancy J.en_US
dc.contributor.authorLomax, Margaret I.en_US
dc.contributor.authorGrossman, Lawrence I.en_US
dc.date.accessioned2006-04-07T20:01:12Z
dc.date.available2006-04-07T20:01:12Z
dc.date.issued1987en_US
dc.identifier.citationBachman, Nancy J., Lomax, Margaret I., Grossman, Lawrence I. (1987)."Two bovine genes for cytochrome c oxidase subunit IV: a processed pseudogene and an expressed gene." Gene 55(2-3): 219-229. <http://hdl.handle.net/2027.42/26919>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T39-47PH8F9-22D/2/bd09441cc55253c1b0dbdc90654eb964en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/26919
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2822541&dopt=citationen_US
dc.description.abstractWe have isolated and analyzed 17 clones from a bovine genomic library in phage [lambda] Charon28 probed with a bovine liver cDNA for cytochrome c oxidase subunit IV. Restriction enzyme mapping and Southern analysis indicated that these clones represent only two genomic regions. One region was shown by nucleotide sequencing to contain a subunit IV pseudogene of the processed type. The other class of clones contained the 5' region of a putative expressed gene; the region consists of two exons and two introns, with one exon encoding exclusively the domain representing the presequence present on newly synthesized subunit-IV polypeptides. Genomic Southern analysis indicated that these two clones probably represent the only sequences in the bovine nucleus that share nucleotide sequence identity with the liver subunit IV cDNA when utilizing moderately stringent hybridization conditions.en_US
dc.format.extent1208288 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleTwo bovine genes for cytochrome c oxidase subunit IV: a processed pseudogene and an expressed geneen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Cellular and Molecular Biology, Division of Biological Sciences, The University of Michigan, Ann Arbor, MI 48109, U.S.Aen_US
dc.contributor.affiliationumDepartment of Cellular and Molecular Biology, Division of Biological Sciences, The University of Michigan, Ann Arbor, MI 48109, U.S.Aen_US
dc.contributor.affiliationumDepartment of Cellular and Molecular Biology, Division of Biological Sciences, The University of Michigan, Ann Arbor, MI 48109, U.S.Aen_US
dc.identifier.pmid2822541en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/26919/1/0000485.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0378-1119(87)90282-4en_US
dc.identifier.sourceGeneen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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