Oxygen metabolite detoxifying enzyme levels in bleomycin-induced fibrotic lungs

Fantone, Joseph C.; Phan, Sem H.

1988

Citation: Fantone, Joseph C., Phan, Sem H. (1988)."Oxygen metabolite detoxifying enzyme levels in bleomycin-induced fibrotic lungs." Free Radical Biology and Medicine 4(6): 399-402. <http://hdl.handle.net/2027.42/27559>

Abstract: The activities of three enzymes cytosolic superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSHP), and malonylialdehyde (MDA), a by-product of lipid peroxidation, were determined in whole lungs of normal and bleomycin-treated rats. Two days after bleomycin treatment total lung SOD, CAT, and GSHP activities were significantly (p p p 2 metabolites may play an important role in the development of bleomycin-induced pulmonary fibrosis.

DOIs: http://dx.doi.org/10.1016/0891-5849(88)90091-3

PMID: 2454874

URI: http://www.sciencedirect.com/science/article/B6T38-47PFTTV-T/2/0085ff31c0773057eedce953612adc3c
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2454874&dopt=citation

Handle: http://hdl.handle.net/2027.42/27559

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