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Drug-reinforced responding: rapid determination of dose-response functions

dc.contributor.authorWinger, Gail D.en_US
dc.contributor.authorPalmer, R. Kyleen_US
dc.contributor.authorWoods, James H.en_US
dc.date.accessioned2006-04-07T20:40:34Z
dc.date.available2006-04-07T20:40:34Z
dc.date.issued1989-10en_US
dc.identifier.citationWinger, G., Palmer, R. K., Woods, J. H. (1989/10)."Drug-reinforced responding: rapid determination of dose-response functions." Drug and Alcohol Dependence 24(2): 135-142. <http://hdl.handle.net/2027.42/27725>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T63-4BWFB65-26/2/6d4a78d518c79f6136881018e33b5780en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/27725
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2676442&dopt=citationen_US
dc.description.abstractRhesus monkeys were conditioned to press on levers and receive intravenous infusions of cocaine or ketamine. Experimental conditions provided several different doses of drug during each of two daily 130 min sessions; as a result, a doseresponse curve relating rate of responding to dose/injection for self-administered drug was obtained within each session. Relative rate-maintaining effects of nomifensine and cocaine in monkeys on baseline conditions of cocaine self-administration, and rate-maintaining effects of ketamine, phencyclidine and MK-801 in monkeys on baseline conditions of ketamine self-administration, compared favorably with relative rate-maintaining effects of these substances obtained in more traditional paradigms.en_US
dc.format.extent696891 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleDrug-reinforced responding: rapid determination of dose-response functionsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelSocial Worken_US
dc.subject.hlbsecondlevelPsychologyen_US
dc.subject.hlbsecondlevelPsychiatryen_US
dc.subject.hlbtoplevelSocial Sciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.contributor.affiliationumDepartment of Psychology, University of Michigan, Ann Arbor, MI 48109, U.S.A.; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, U.S.A.en_US
dc.identifier.pmid2676442en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/27725/1/0000117.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0376-8716(89)90076-8en_US
dc.identifier.sourceDrug and Alcohol Dependenceen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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