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Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis

dc.contributor.authorBecker, Jill B.en_US
dc.date.accessioned2006-04-10T13:35:09Z
dc.date.available2006-04-10T13:35:09Z
dc.date.issued1990-10-16en_US
dc.identifier.citationBecker, Jill B. (1990/10/16)."Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis." Neuroscience Letters 118(2): 169-171. <http://hdl.handle.net/2027.42/28348>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T0G-485RPVH-2CC/2/c1634b9a9a6f069d76dfda11dd193ef0en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/28348
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2125712&dopt=citationen_US
dc.description.abstractOvariectomy (OVX) of female rats results in a decreased behavioral response to stimulation of the mesostriatal dopamine (DA) system and decreased striatal DA release in vitro. Estrogen replacement restores both behavioral and neurochemical responsiveness. In this report, microdialysis in freely moving rats is used to simultaneously study the behavioral and neurochemical effects of systemic estradiol. OVX rats received a unilateral 6-hydroxy-dopamine lesion of the substantia nigra and then underwent microdialysis of the intact striatum. Thirty min after a single injection of 5 [mu]g estradiol benzoate, amphetamine-induced rotational behavior and striatal DA release are both potentiated, relative to the response of oil-treated control animals.en_US
dc.format.extent253146 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleEstrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysisen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelPsychologyen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelSocial Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumPsychology Department and Neuroscience Program, The University of Michigan, Ann Arbor, MI 48104-1687, U.S.A.en_US
dc.identifier.pmid2125712en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/28348/1/0000109.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0304-3940(90)90618-Jen_US
dc.identifier.sourceNeuroscience Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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