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Effect of electrical stimulation on middle latency response in the guinea pig

dc.contributor.authorCannon, Stephen C.en_US
dc.contributor.authorMiller, Josef M.en_US
dc.contributor.authorCrowther, John A.en_US
dc.contributor.authorMoscow, Danen_US
dc.date.accessioned2006-04-10T13:41:19Z
dc.date.available2006-04-10T13:41:19Z
dc.date.issued1990en_US
dc.identifier.citationCannon, Stephen C., Miller, Josef M., Crowther, John, Moscow, Dan (1990)."Effect of electrical stimulation on middle latency response in the guinea pig." American Journal of Otolaryngology 11(4): 251-255. <http://hdl.handle.net/2027.42/28502>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6W9S-4C0DR30-N6/2/1451c77822303b6f2937c5244b93e77ben_US
dc.identifier.urihttps://hdl.handle.net/2027.42/28502
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2240413&dopt=citationen_US
dc.description.abstractA temporary threshold shift (TTS) has been demonstrated in the electrically evoked middle latency response (EMLR) following exposure to moderate levels of continuous electrical stimulation via a cochlear implant. The threshold at which the EMLR was elicited in chronically implanted guinea pigs was elevated by approximately 100% following 30 minutes of moderate intensity (200 [mu]A or more) sinusoidal electrical stimulation of the cochlea. Results obtained under anesthesia varied unacceptably. In awake animals, EMLR thresholds were stable over time and consistant TTSs were observed. The threshold returned to prestimulation levels within 4 hours following termination of the stimulation. The possibility of histopathologic changes and the relevance of these findings in setting safe output levels for cochlear implant processors are discussed.en_US
dc.format.extent615678 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleEffect of electrical stimulation on middle latency response in the guinea pigen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelSurgery and Anesthesiologyen_US
dc.subject.hlbsecondlevelOtolaryngologyen_US
dc.subject.hlbsecondlevelDentistryen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan, Kresge Hearing Research Institute, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumUniversity of Michigan, Kresge Hearing Research Institute, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumUniversity of Michigan, Kresge Hearing Research Institute, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumUniversity of Michigan, Kresge Hearing Research Institute, Ann Arbor, MI, USAen_US
dc.identifier.pmid2240413en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/28502/1/0000299.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0196-0709(90)90085-Aen_US
dc.identifier.sourceAmerican Journal of Otolaryngologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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