T cell receptor [beta]-chain gene rearrangement without [gamma]-chain gene rearrangement in cutaneous T cell lymphoma: An unusual finding

Ho, Vincent C.; Hansen, Erik R.; Elder, James T.; Baadsgaard, Ole; Vejlsgaard, Gunhild L.; Hanson, Curtis A.; Cooper, Kevin D.

1990-03

Citation: Ho, Vincent C., Hansen, Erik R., Elder, James T., Baadsgaard, Ole, Vejlsgaard, Gunhild L., Hanson, Curtis A., Cooper, Kevin D. (1990/03)."T cell receptor [beta]-chain gene rearrangement without [gamma]-chain gene rearrangement in cutaneous T cell lymphoma: An unusual finding." Clinical Immunology and Immunopathology 54(3): 354-360. <http://hdl.handle.net/2027.42/28714>

Abstract: T cells from the blood and skin of a patient with cutaneous T cell lymphoma demonstrated rearrangement of the T cell receptor [beta]-chain gene in the absence of rearrangement of the [gamma]-chain gene. To our knowledge, this has not been previously reported. This finding was unexpected in light of prevailing concepts of T cell ontogeny. Potential explanations for it are discussed.

DOIs: http://dx.doi.org/10.1016/0090-1229(90)90049-V

PMID: 2154349

URI: http://www.sciencedirect.com/science/article/B6WCK-4BJW3W4-1M8/2/ffa7f638d3286f9ad0f7e383eed6e044
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2154349&dopt=citation

Handle: http://hdl.handle.net/2027.42/28714

Show full item record