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The effect of noise exposure on the aging ear

dc.contributor.authorShone, Geoffreyen_US
dc.contributor.authorAltschuler, Richard A.en_US
dc.contributor.authorMiller, Josef M.en_US
dc.contributor.authorNuttall, Alfred L.en_US
dc.date.accessioned2006-04-10T14:31:43Z
dc.date.available2006-04-10T14:31:43Z
dc.date.issued1991-11en_US
dc.identifier.citationShone, Geoffrey, Altschuler, Richard A., Miller, Josef M., Nuttall, Alfred L. (1991/11)."The effect of noise exposure on the aging ear." Hearing Research 56(1-2): 173-178. <http://hdl.handle.net/2027.42/29048>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T73-485PD87-9W/2/e9715c330e59b15eb29bddb7dca7e79aen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/29048
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1769911&dopt=citationen_US
dc.description.abstractThe effect of noise exposure on auditory sensitivity and inner ear morphology was compared in aged and young mature mice. Hearing thresholds were obtained by auditory evoked brain stem responses (ABR) before and after noise exposure, and hair cell loss was quantified. The study was done in two parts: first to assess the effect of noise exposure on subjects with presbycusis, and second to assess its effect on aged subjects without measurable presbycusis. In the first experiment C57BL/6 mice, with an age-related hearing loss, were used as a model for presbycusis. C57BL/6 mice exhibiting presbycusis were more susceptible to noise injury than age-matched CBA/Ca mice. In the second experiment CBA/Ca mice were used. These mice retain normal hearing even with advancing age. The aged CBA/Ca mice had the same susceptibility to noise injury as young CBA/Ca mice.en_US
dc.format.extent738469 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleThe effect of noise exposure on the aging earen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumKresge Hearing Research Institute, The University of Michigan, Ann Arbor, Michigan, U.S.A.en_US
dc.contributor.affiliationumKresge Hearing Research Institute, The University of Michigan, Ann Arbor, Michigan, U.S.A.en_US
dc.contributor.affiliationumKresge Hearing Research Institute, The University of Michigan, Ann Arbor, Michigan, U.S.A.en_US
dc.contributor.affiliationumKresge Hearing Research Institute, The University of Michigan, Ann Arbor, Michigan, U.S.A.en_US
dc.identifier.pmid1769911en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/29048/1/0000081.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0378-5955(91)90167-8en_US
dc.identifier.sourceHearing Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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