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Isolation of a yeast artificial chromosome clone that spans the (12;16) translocation breakpoint characteristic of myxoid liposarcoma

dc.contributor.authorGemmill, Robert M.en_US
dc.contributor.authorMendez, Michael J.en_US
dc.contributor.authorDougherty, Cynthia M.en_US
dc.contributor.authorPaulien, Sylvieen_US
dc.contributor.authorLiao, Marthaen_US
dc.contributor.authorMitchell, Deannaen_US
dc.contributor.authorJankowski, Sheryl A.en_US
dc.contributor.authorTrent, Jeffrey M.en_US
dc.contributor.authorBerger, Carol S.en_US
dc.contributor.authorSandberg, Avery A.en_US
dc.contributor.authorMeltzer, Paul S.en_US
dc.date.accessioned2006-04-10T15:05:41Z
dc.date.available2006-04-10T15:05:41Z
dc.date.issued1992-09en_US
dc.identifier.citationGemmill, Robert M., Mendez, Michael J., Dougherty, Cynthia M., Paulien, Sylvie, Liao, Martha, Mitchell, Deanna, Jankowski, Sheryl A., Trent, Jeffrey M., Berger, Carol, Sandberg, Avery A., Meltzer, Paul S. (1992/09)."Isolation of a yeast artificial chromosome clone that spans the (12;16) translocation breakpoint characteristic of myxoid liposarcoma." Cancer Genetics and Cytogenetics 62(2): 166-170. <http://hdl.handle.net/2027.42/29862>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T53-47PYBK6-4X/2/70e17e419929449d4e873c01805761bcen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/29862
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1394104&dopt=citationen_US
dc.description.abstractCytogenetic analysis of liposarcomas has demonstrated that translocation (12;16) (q13.3;p11.2) is characteristic of the myxoid subtype of this adipose tissue tumor. Our previous results suggested that the GLI gene is close to the translocation breakpoint on chromosome 12. We now describe a yeast artificial chromosome (YAC) that contains GLI and spans the chromosome 12 region involved in the t(12;16) breakpoint. This clone will permit rapid definition of the genetic region surrounding the breakpoint and allow isolation of the gene presumably affected by the translocation.en_US
dc.format.extent433784 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleIsolation of a yeast artificial chromosome clone that spans the (12;16) translocation breakpoint characteristic of myxoid liposarcomaen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelOncology and Hematologyen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialtiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA; Eleanor Roosevelt Institute, Denver, Colorado, USA.en_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA.en_US
dc.contributor.affiliationumDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA.en_US
dc.contributor.affiliationotherSouthwest Biomedical Research Institute, Scottsdale, Arizona, USA.en_US
dc.contributor.affiliationotherSouthwest Biomedical Research Institute, Scottsdale, Arizona, USA.en_US
dc.identifier.pmid1394104en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/29862/1/0000210.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0165-4608(92)90257-9en_US
dc.identifier.sourceCancer Genetics and Cytogeneticsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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