Variability of laser-evoked potentials: attention, arousal and lateralized differences
dc.contributor.author | Beydoun, Ahmad A. | en_US |
dc.contributor.author | Morrow, Thomas J. | en_US |
dc.contributor.author | Shen, Joanne F. | en_US |
dc.contributor.author | Casey, Kenneth L. | en_US |
dc.date.accessioned | 2006-04-10T15:46:07Z | |
dc.date.available | 2006-04-10T15:46:07Z | |
dc.date.issued | 1993 | en_US |
dc.identifier.citation | Beydoun, Ahmad, Morrow, Thomas J., Shen, Joanne F., Casey, Kenneth L. (1993)."Variability of laser-evoked potentials: attention, arousal and lateralized differences." Electroencephalography and Clinical Neurophysiology/Evoked Potentials Section 88(3): 173-181. <http://hdl.handle.net/2027.42/30809> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6SYY-482XX8R-33/2/65776118a0a3b13c574c6815becf12ca | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/30809 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7684966&dopt=citation | en_US |
dc.description.abstract | We recorded laser-evoked potentials (LEPs) from 20 normal subjects by stimulating the skin with pulses from an infrared CO2 laser. The conduction velocity of the peripheral afferent fibers mediating the LEPs averaged 14.9 m/sec. The amplitude of the LEP components correlated significantly with perceived stimulus intensity. During repetitive constant intensity stimulation, the peak-to-peak LEP amplitude decreased 38% during a distraction task and 42% during drowsiness and was absent during stage 2 sleep, indicating a modulation of responsiveness to laser stimulation during distraction and decreased states of arousal. Normative data revealed considerable intersubject variability in LEP latencies and amplitudes. Analysis of intrasubject lateralized (side-to-side) differences revealed that the relative peak-to-peak amplitude was less variable than that of the N or P components. For clinical applications using 3 S.D.s to define the normal range, a lateral interpeak amplitude difference greater than 28% would suggest focal or lateralized sensory abnormality in an individual patient. Vigilance and attentiveness to the stimuli should be monitored during the acquisition of LEPs. | en_US |
dc.format.extent | 826532 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Variability of laser-evoked potentials: attention, arousal and lateralized differences | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Neurology Research Laboratories, Veterans Administration Medical Center, Ann Arbor, MI, USA. | en_US |
dc.contributor.affiliationum | Neurology Research Laboratories, Veterans Administration Medical Center, Ann Arbor, MI, USA; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA. | en_US |
dc.contributor.affiliationum | Neurology Research Laboratories, Veterans Administration Medical Center, Ann Arbor, MI, USA; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA. | en_US |
dc.contributor.affiliationum | Neurology Research Laboratories, Veterans Administration Medical Center, Ann Arbor, MI, USA; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA. | en_US |
dc.identifier.pmid | 7684966 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/30809/1/0000467.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0168-5597(93)90002-7 | en_US |
dc.identifier.source | Electroencephalography and Clinical Neurophysiology/Evoked Potentials Section | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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