Axotomy increases CNTF receptor mRNA in rat spinal cord

Mata, Marina; Jin, Chuan-Fang; Fink, David J.

1993-04-30

Citation: Mata, Marina, Jin, Chuan-Fang, Fink, David J. (1993/04/30)."Axotomy increases CNTF receptor mRNA in rat spinal cord." Brain Research 610(1): 162-165. <http://hdl.handle.net/2027.42/30830>

Abstract: In order to study the role of ciliary neurotrophic factor (CNTF) and its receptor (CNTF-R) in the response of spinal cord neurons to axotomy, we measured the levels of CNTF mRNA in nerve and CNTF-R mRNA in spinal cord following transection of sciatic nerve, using reverse transcriptase PCR. We found CNTF mRNA levels in the nerve fell and that CNTF-R mRNA levels in spinal cord increased at both 1 and 7 days following transection.

DOIs: http://dx.doi.org/10.1016/0006-8993(93)91231-G

PMID: 8390909

URI: http://www.sciencedirect.com/science/article/B6SYR-4840N5J-1DP/2/afc25a42770a6f7c69620a3eb766eff1
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8390909&dopt=citation

Handle: http://hdl.handle.net/2027.42/30830

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