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Protein tyrosine phosphatases in disease processes

dc.contributor.authorNinfa, Elizabeth G.en_US
dc.contributor.authorDixon, Jack E.en_US
dc.date.accessioned2006-04-10T17:43:39Z
dc.date.available2006-04-10T17:43:39Z
dc.date.issued1994-12en_US
dc.identifier.citationNinfa, Elizabeth G., Dixon, Jack E. (1994/12)."Protein tyrosine phosphatases in disease processes." Trends in Cell Biology 4(12): 427-430. <http://hdl.handle.net/2027.42/31159>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6TCX-47GGPK5-3C/2/edd90436772710b3f61601612bf36befen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/31159
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=14731691&dopt=citationen_US
dc.description.abstractGiven the importance of tyrosine phosphorylation of proteins in signalling pathways, it is perhaps not surprising that protein tyrosine phosphatases (PTPs) are involved in the pathogenesis of certain human diseases. A PTP produced by the Yersinia bacteria (which can cause bubonic plague, septicemia and enteric diseases) is thought to be used as a `weapon' against host cell functions. In addition, dysfunction of cells' endogenous PTPs may contribute to defective immune function, to cancer and to diabetes.en_US
dc.format.extent425446 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleProtein tyrosine phosphatases in disease processesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biological Chemistry, The University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationumDepartment of Biological Chemistry, The University of Michigan, Ann Arbor, MI 48109, USAen_US
dc.identifier.pmid14731691en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/31159/1/0000058.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0962-8924(94)90103-1en_US
dc.identifier.sourceTrends in Cell Biologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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