Glutathione and morbidity in a community-based sample of elderly
dc.contributor.author | Julius, Mara | en_US |
dc.contributor.author | Lang, Calvin A. | en_US |
dc.contributor.author | Gleiberman, Lillian | en_US |
dc.contributor.author | Harburg, Ernest | en_US |
dc.contributor.author | DiFranceisco, Wayne | en_US |
dc.contributor.author | Schork, Anthony | en_US |
dc.date.accessioned | 2006-04-10T17:56:51Z | |
dc.date.available | 2006-04-10T17:56:51Z | |
dc.date.issued | 1994-09 | en_US |
dc.identifier.citation | Julius, Mara, Lang, Calvin A., Gleiberman, Lillian, Harburg, Ernest, Difranceisco, Wayne, Schork, Anthony (1994/09)."Glutathione and morbidity in a community-based sample of elderly." Journal of Clinical Epidemiology 47(9): 1021-1026. <http://hdl.handle.net/2027.42/31377> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T84-4BTY1D2-Y/2/6c59931f4b328c32ea62501750c89e07 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/31377 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7730904&dopt=citation | en_US |
dc.description.abstract | This study examined the association of blood glutathione level, a potential marker of physiological/functional aging, with a number of biomedical/psychological traits in a subgroup (N = 33) of a representative sample of community-based elderly. Higher glutathione levels were associated with fewer number of illnesses (p p p < 0.05), lower body mass index, and lower blood pressures. Subjects with diagnoses of arthritis, diabetes, or heart disease (as assessed by physicians) had at least marginally significant lower glutathione levels than those who were disease free. Glutathione, together with age and a measure of suppressed anger, accounted for 39% of the variance of an index of morbidity. Glutathione, by itself, accounted for 24% of the variance. To our knowledge, this is the first evidence of an association of higher glutathione levels with higher levels of physical health in a sample of community-based elderly. Further studies in large samples are needed to investigate glutathione as a potential overall health risk factor for morbidity among the elderly. | en_US |
dc.format.extent | 615885 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Glutathione and morbidity in a community-based sample of elderly | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Psychology, School of Literature, Science and the Arts, University of Michigan, MI 48109, USA | en_US |
dc.contributor.affiliationum | Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA | en_US |
dc.contributor.affiliationother | Department of Biochemistry, School of Medicine, University of Louisville, Louisville, KY 40292, USA | en_US |
dc.contributor.affiliationother | Department of Biostatistics, School of Public Health, University of, Michigan, MI 48109, U.S.A. | en_US |
dc.identifier.pmid | 7730904 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/31377/1/0000290.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0895-4356(94)90117-1 | en_US |
dc.identifier.source | Journal of Clinical Epidemiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.