The influence of particle size of liposomes on the deposition of drug into skin
dc.contributor.author | du Plessis, Jeanetta | en_US |
dc.contributor.author | Ramachandran, Chandrasekharan | en_US |
dc.contributor.author | Weiner, Norman D. | en_US |
dc.contributor.author | Muller, D. G. | en_US |
dc.date.accessioned | 2006-04-10T18:16:33Z | |
dc.date.available | 2006-04-10T18:16:33Z | |
dc.date.issued | 1994-03-30 | en_US |
dc.identifier.citation | du Plessis, J., Ramachandran, C., Weiner, N., Muller, D. G. (1994/03/30)."The influence of particle size of liposomes on the deposition of drug into skin." International Journal of Pharmaceutics 103(3): 277-282. <http://hdl.handle.net/2027.42/31700> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T7W-475547C-12V/2/68248130be5d56c94e89f8eea6b98a64 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/31700 | |
dc.description.abstract | The effect of particle size of liposomes on the deposition of drugs into the strata of skin was evaluated using hairless mice, hamster and pig skin. In vitro diffusion studies were performed in an attempt to find an optimum formulation for topical drug delivery as well as to try to explain the mechanism of topical drug delivery by liposomes. The results indicate that an optimum particle size for optimal drug delivery exists. The study proved that the follicular route play an important role in determining the kinetics of drug transfer from liposomes into the skin. | en_US |
dc.format.extent | 613799 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | The influence of particle size of liposomes on the deposition of drug into skin | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy, University of Michigan, MI, USA | en_US |
dc.contributor.affiliationum | College of Pharmacy, University of Michigan, MI, USA | en_US |
dc.contributor.affiliationother | Department of Pharmaceutics, Potchefstroom University for CHE, Potchefstroom, South Africa | en_US |
dc.contributor.affiliationother | Department of Pharmaceutics, Potchefstroom University for CHE, Potchefstroom, South Africa | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/31700/1/0000636.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0378-5173(94)90178-3 | en_US |
dc.identifier.source | International Journal of Pharmaceutics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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