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Effects of benzothiadiazine drugs on carbohydrate metabolism

dc.contributor.authorWeller, John M.en_US
dc.contributor.authorBorondy, Paul E.en_US
dc.date.accessioned2006-04-13T14:42:42Z
dc.date.available2006-04-13T14:42:42Z
dc.date.issued1965-06en_US
dc.identifier.citationWeller, John M., Borondy, Paul E. (1965/06)."Effects of benzothiadiazine drugs on carbohydrate metabolism." Metabolism 14(6): 708-714. <http://hdl.handle.net/2027.42/32021>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WN4-4C4FJBV-6P/2/f145f5c33b4cacb25930859c1716de87en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/32021
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=14293526&dopt=citationen_US
dc.description.abstractThe administration of chlorothiazide both to man and to rats results in hyperglycemia following a glucose load. Its administration to rats causes a decreased rate of glucose utilization by their adipose tissue in vitro. Chlorothiazide added directly to the incubating medium also decreases the rate of glucose utilization of rat adipose tissue. These effects of chlorothiazide are most likely due to both a direct action of the drug on tissue glucose metabolism and an indirect effect which is the result of chlorothiazide causing a decrease in the level of serum insulin-like activity which in turn diminishes the activity of insulin-dependent enzymes involved in glucose metabolism.en_US
dc.format.extent537056 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleEffects of benzothiadiazine drugs on carbohydrate metabolismen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumProfessor of Internal Medicine, University of Michigan Medical School, Ann Arbor, Mich., USAen_US
dc.contributor.affiliationumResearch Assistant, University of Michigan Medical School, Ann Arbor, Mich., USAen_US
dc.identifier.pmid14293526en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/32021/1/0000063.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0026-0495(65)90054-5en_US
dc.identifier.sourceMetabolismen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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