Two cases of changes in amino acid transport activity with tissue development

Abstract

During the first day of extrauterine life the liver of the guinea-pig greatly intensifies the extent of the steady-state concentration of two amino acids, one normal and one non-metabolizable. Another change with tissue development is in the reverse direction, namely the loss of two or more uphill transport systems by the rabbit reticulocyte on its maturation. The nature of the association between changes in the character and intensity of protein synthesis and in amino acid transport activity, as illustrated by these two cases, is discussed.