Platelets and thrombogenesis--Current concepts
dc.contributor.author | Schnetzer, III, George W. | en_US |
dc.date.accessioned | 2006-04-17T16:50:40Z | |
dc.date.available | 2006-04-17T16:50:40Z | |
dc.date.issued | 1972-04 | en_US |
dc.identifier.citation | Schnetzer, III, George W. (1972/04)."Platelets and thrombogenesis--Current concepts." American Heart Journal 83(4): 552-564. <http://hdl.handle.net/2027.42/34128> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6W9H-4BK9SP9-BN/2/5e9d64332ab5ac53d54497b8d5c5691d | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/34128 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4339454&dopt=citation | en_US |
dc.description.abstract | Anticoagulants, although effective in the treatment of venous thrombotic disease, have not been generally helpful in preventing arterial thrombosis. The reason for this disparity may lie in the type of clot formed in each case. In veins a "red thrombus" is formed, consisting of erythrocytes, leukocytes, fibrin, and platelets randomly distributed, whereas in arteries a "white thrombus" consisting mainly of platelets and fibrin strands is the obstructing lesion1. The predominance of platelets in this "white" clot has focused attention on their importance in arterial occlusion and has suggested that therapeutic maneuvers directed at platelet function may be more useful than standard anticoagulant therapy. This review presents the recent advances in the study of platelet morphology and function, and concludes by discussing possible therapeutic avenues. | en_US |
dc.format.extent | 3461312 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Platelets and thrombogenesis--Current concepts | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Internal Medicine (Simpson Memorial Institute), University of Michigan, Ann Arbor, Mich., USA | en_US |
dc.identifier.pmid | 4339454 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/34128/1/0000412.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0002-8703(72)90048-8 | en_US |
dc.identifier.source | American Heart Journal | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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