Group sequential monitoring of years of life saved with paired censored survival data
dc.contributor.author | Murray, Susan | en_US |
dc.date.accessioned | 2006-04-19T13:54:38Z | |
dc.date.available | 2006-04-19T13:54:38Z | |
dc.date.issued | 2002-01-30 | en_US |
dc.identifier.citation | Murray, Susan (2002)."Group sequential monitoring of years of life saved with paired censored survival data." Statistics in Medicine 21(2): 177-189. <http://hdl.handle.net/2027.42/34859> | en_US |
dc.identifier.issn | 0277-6715 | en_US |
dc.identifier.issn | 1097-0258 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/34859 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=11782058&dopt=citation | en_US |
dc.description.abstract | This research develops non-parametric methodology for sequential monitoring of paired time-to-event data when comparing years of life saved, or years where any unpleasant outcome is delayed, is of interest. The recommended family of test statistics uses integrated differences in survival estimates that are available during the study period, where adjustments are made for dependence in the survival and censoring outcomes under comparison. In the context of paired censored survival data, the joint asymptotic closed form distribution of these sequentially monitored test statistics is developed and shown to have a dependent increments structure. Simulations verifying nice operating characteristics of the proposed monitoring methods also reveal consequences of ignoring an underlying paired data structure in terms of size and power properties. A motivating example is also presented via the Early Treatment Diabetic Retinopathy Study, which did not have methods available for sequentially monitoring paired censored survival data at the time. Copyright © 2002 John Wiley & Sons, Ltd. | en_US |
dc.format.extent | 131456 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | John Wiley & Sons, Ltd. | en_US |
dc.subject.other | Mathematics and Statistics | en_US |
dc.title | Group sequential monitoring of years of life saved with paired censored survival data | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbsecondlevel | Statistics and Numeric Data | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Social Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, U.S.A. ; Department of Biostatistics, University of Michigan, 1420 Washington Heights, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.identifier.pmid | 11782058 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/34859/1/990_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/sim.990 | en_US |
dc.identifier.source | Statistics in Medicine | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.