Mitochondrial versus nuclear admixture estimates demonstrate a past history of directional mating
dc.contributor.author | Merriwether, D. Andrew | en_US |
dc.contributor.author | Huston, Sara | en_US |
dc.contributor.author | Iyengar, Sudha | en_US |
dc.contributor.author | Hamman, Richard | en_US |
dc.contributor.author | Norris, Jill M. | en_US |
dc.contributor.author | Shetterly, Susan M. | en_US |
dc.contributor.author | Kamboh, M. Ilyas | en_US |
dc.contributor.author | Ferrell, Robert E. | en_US |
dc.date.accessioned | 2006-04-28T16:19:00Z | |
dc.date.available | 2006-04-28T16:19:00Z | |
dc.date.issued | 1997-02 | en_US |
dc.identifier.citation | Merriwether, D. Andrew; Huston, Sara; Iyengar, Sudha; Hamman, Richard; Norris, Jill M.; Shetterly, Susan M.; Kamboh, M. Ilyas; Ferrell, Robert E. (1997)."Mitochondrial versus nuclear admixture estimates demonstrate a past history of directional mating." American Journal of Physical Anthropology 102(2): 153-159. <http://hdl.handle.net/2027.42/37680> | en_US |
dc.identifier.issn | 0002-9483 | en_US |
dc.identifier.issn | 1096-8644 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/37680 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9066897&dopt=citation | en_US |
dc.description.abstract | Six blood group antigens (ABO, RH, MNS, KK, KP, FY) and five plasma proteins (HP, GC, APOA4, FXIIIB, C1R) were typed in 790 individuals, and 12 mtDNA RFLP and deletion polymorphisms were typed in 657 individuals from the San Luis Valley, Colorado. The 790 nuclear typings were conducted on 399 Anglos and 391 Hispanics, while the 657 mitochondrial haplotypes were generated from 207 Anglos and 450 Hispanics. Chakraborty's ADMIX2 FORTRAN program was used to estimate the average Amerindian admixture using all nuclear loci simultaneously. Since there is no recombination in mtDNA, the sum of the frequencies of the Amerindian/Asian-specific mitochondrial haplotypes represents the level of Amerindian admixture. The nuclear estimates of Amerindian admixture were 33.15 ± 2.41% for the Hispanics and 9.72 ± 1.90% for the Anglos, while the strictly maternally inherited mtDNA estimates of Amerindian admixture were 85.11% for the Hispanics and 0.97% for the Anglos. This dramatic difference in estimated levels of admixture between the biparentally derived nuclear estimates and the uniparentally derived mtDNA estimates is indicative of past directional matings between Hispanic males and Amerindian females. Am J Phys Anthropol 102:153–159 © 1997 Wiley-Liss, Inc. | en_US |
dc.format.extent | 454830 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Anthropology | en_US |
dc.title | Mitochondrial versus nuclear admixture estimates demonstrate a past history of directional mating | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Anthropology | en_US |
dc.subject.hlbtoplevel | Social Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Anthropology, University of Michigan, Ann Arbor, Michigan 48109 ; Department of Anthropology, University of Michigan, 1054 LSA Building, Ann Arbor, MI 48109 | en_US |
dc.contributor.affiliationother | Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 | en_US |
dc.contributor.affiliationother | Department of Genetics, Yale University, New Haven, Connecticut 06520 | en_US |
dc.contributor.affiliationother | Department of Preventative Medicine and Biometrics, University of Colorado School of Medicine, Denver, Colorado 80262 | en_US |
dc.contributor.affiliationother | Department of Preventative Medicine and Biometrics, University of Colorado School of Medicine, Denver, Colorado 80262 | en_US |
dc.contributor.affiliationother | Department of Preventative Medicine and Biometrics, University of Colorado School of Medicine, Denver, Colorado 80262 | en_US |
dc.contributor.affiliationother | Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 | en_US |
dc.contributor.affiliationother | Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 | en_US |
dc.identifier.pmid | 9066897 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/37680/1/1_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/(SICI)1096-8644(199702)102:2<153::AID-AJPA1>3.0.CO;2-# | en_US |
dc.identifier.source | American Journal of Physical Anthropology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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