Increase in CD5+ B Cells in Juvenile Rheumatoid Arthritis
dc.contributor.author | Jarvis, James N. | en_US |
dc.contributor.author | Kaplan, Joseph | en_US |
dc.contributor.author | Fine, Nancy | en_US |
dc.date.accessioned | 2006-04-28T16:24:43Z | |
dc.date.available | 2006-04-28T16:24:43Z | |
dc.date.issued | 1992-02 | en_US |
dc.identifier.citation | Jarvis, James N.; Kaplan, Joseph; Fine, Nancy (1992)."Increase in CD5+ B Cells in Juvenile Rheumatoid Arthritis." Arthritis & Rheumatism 35(2): 204-207. <http://hdl.handle.net/2027.42/37790> | en_US |
dc.identifier.issn | 0004-3591 | en_US |
dc.identifier.issn | 1529-0131 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/37790 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1370899&dopt=citation | en_US |
dc.description.abstract | Objective. To investigate the association between CD5+ B cell expression and IgM rheumatoid factor (IgM-RF) in juvenile rheumatoid arthritis (JRA). Methods. CD5+ B cell levels analyzed by flow cytometry and IgM-RF expression determined by enzymelinked immunosorbent assay were compared in children with JRA, children with other collagen vascular diseases, and healthy controls. Results. Children with polyarticular JRA had expanded populations of CD5+ B cells, and expansion of CD5+ B cells and IgM-RF both correlated with disease activity. Conclusion. The results indicate that an expanded CD5+ B cell population leads to IgM-RF production in patients with polyarticular JRA, as well as patients with RA. | en_US |
dc.format.extent | 381372 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | John Wiley & Sons, Inc. | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Rheumatology | en_US |
dc.title | Increase in CD5+ B Cells in Juvenile Rheumatoid Arthritis | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Geriatrics | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationother | Department of Pediatrics, the Division of Rheumatology, and the Division of Tumor Immunology, Wayne State University School of Medicine, and the Children's Hospital of Michigan, Detroit. ; Department of Immunology and Rheumatology, Children's Hospital of Michigan, 3901 Beaubien Boulevard, Detroit, MI 48201 | en_US |
dc.contributor.affiliationother | Department of Pediatrics, the Division of Rheumatology, and the Division of Tumor Immunology, Wayne State University School of Medicine, and the Children's Hospital of Michigan, Detroit. | en_US |
dc.contributor.affiliationother | Department of Pediatrics, the Division of Rheumatology, and the Division of Tumor Immunology, Wayne State University School of Medicine, and the Children's Hospital of Michigan, Detroit. | en_US |
dc.identifier.pmid | 1370899 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/37790/1/1780350213_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/art.1780350213 | en_US |
dc.identifier.source | Arthritis & Rheumatism | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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