Frog lysozyme. I. Its identification, occurrence as isozymes, and quantitative distribution in tissues of the leopard frog, Rana pipiens Contribution No. 64 from the Amphibian Facility. , The animals used in this study were maintained in facilities that are fully accredited by the American Association for Accreditation of Laboratory Animal Care (AAALAC).
dc.contributor.author | Ostrovsky, David S. | en_US |
dc.contributor.author | Snyder, John A. | en_US |
dc.contributor.author | Iwata, Takuzo | en_US |
dc.contributor.author | Izaka, Ken-Ichi | en_US |
dc.contributor.author | Maglott, Donna S. | en_US |
dc.contributor.author | Nace, George W. | en_US |
dc.date.accessioned | 2006-04-28T16:39:02Z | |
dc.date.available | 2006-04-28T16:39:02Z | |
dc.date.issued | 1976-02 | en_US |
dc.identifier.citation | Ostrovsky, David S.; Snyder, John A.; Iwata, Takuzo; Izaka, Ken-Ichi; Maglott, Donna S.; Nace, George W. (1976)."Frog lysozyme. I. Its identification, occurrence as isozymes, and quantitative distribution in tissues of the leopard frog, Rana pipiens Contribution No. 64 from the Amphibian Facility. , The animals used in this study were maintained in facilities that are fully accredited by the American Association for Accreditation of Laboratory Animal Care (AAALAC). ." Journal of Experimental Zoology 195(2): 279-290. <http://hdl.handle.net/2027.42/38075> | en_US |
dc.identifier.issn | 0022-104X | en_US |
dc.identifier.issn | 1097-010X | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/38075 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4576&dopt=citation | en_US |
dc.description.abstract | In the course of examining the etiology of the LuckÉ renal adenocarcinoma of the frog, Rana pipiens , it was found that organs of the normal adult contain bacteriolytic enzymes. These enzymes all satisfied the six criteria for the identification of lysozymes and at least eight forms were separable by polyacrylamide gel electrophoresis. Their qualitative and quantitative distribution was organ-specific. All eight isozymes were found in normal kidney, while liver and spleen contained seven forms; skin, six; ovarian egg, five; and serum, two. In quantitative assays using a radial diffusion test, spleen had the greatest lysozyme concentration, followed in descending order by kidney, liver, skin, and ovary. Serum contained very low amounts. In terms of enzyme activity per animal, ovary was the highest ranking organ. As such a large number of lysozyme isozymes has not been reported in any other organism, their origins and functions are considered in the context of their presence in an ectotherm. | en_US |
dc.format.extent | 1017694 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cell & Developmental Biology | en_US |
dc.title | Frog lysozyme. I. Its identification, occurrence as isozymes, and quantitative distribution in tissues of the leopard frog, Rana pipiens Contribution No. 64 from the Amphibian Facility. , The animals used in this study were maintained in facilities that are fully accredited by the American Association for Accreditation of Laboratory Animal Care (AAALAC). | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 ; Adapted, in part, from dissertations submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy, The University of Michigan. | en_US |
dc.contributor.affiliationum | Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Division of Biological Sciences and Center for Human Growth and Development, The University of Michigan, Ann Arbor, Michigan 48109 ; Division of Biological Sciences, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.identifier.pmid | 4576 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/38075/1/1401950213_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/jez.1401950213 | en_US |
dc.identifier.source | Journal of Experimental Zoology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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