Improved sib-pair linkage test for disease susceptibility loci
dc.contributor.author | Faraway, Julian J. | en_US |
dc.date.accessioned | 2006-04-28T17:01:29Z | |
dc.date.available | 2006-04-28T17:01:29Z | |
dc.date.issued | 1993 | en_US |
dc.identifier.citation | Faraway, Julian J. (1993)."Improved sib-pair linkage test for disease susceptibility loci." Genetic Epidemiology 10(4): 225-233. <http://hdl.handle.net/2027.42/38504> | en_US |
dc.identifier.issn | 0741-0395 | en_US |
dc.identifier.issn | 1098-2272 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/38504 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8224803&dopt=citation | en_US |
dc.description.abstract | An improved sib-pair test for linkage is introduced which is superior to the previously proposed tests. The test is derived from the standard chi-squared goodness of fit statistic by restricting the alternative hypothesis to the genetically possible. Critical values are given and exact power comparisons are made with the previously proposed tests. The new test is shown to be more powerful for finite samples as well as being asymptotically uniformly most powerful. © 1993 Wiley-Liss, Inc. | en_US |
dc.format.extent | 406147 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Genetics | en_US |
dc.title | Improved sib-pair linkage test for disease susceptibility loci | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbsecondlevel | Genetics | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Statistics, University of Michigan, Ann Arbor ; Department of Statistics, University of Michigan, Ann Arbor, MI 48109 | en_US |
dc.identifier.pmid | 8224803 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/38504/1/1370100403_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/gepi.1370100403 | en_US |
dc.identifier.source | Genetic Epidemiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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