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Comparison of Human Duodenum and Caco-2 Gene Expression Profiles for 12,000 Gene Sequences Tags and Correlation with Permeability of 26 Drugs

dc.contributor.authorWelage, Lynda S.en_US
dc.contributor.authorFleisher, Daviden_US
dc.contributor.authorLandowski, Christopher P.en_US
dc.contributor.authorLennernas, Hansen_US
dc.contributor.authorAmidon, Gordon L.en_US
dc.contributor.authorBarnett, Jeffrey L.en_US
dc.contributor.authorFoster, Daviden_US
dc.contributor.authorLee, Kyung-Dallen_US
dc.contributor.authorSun, Duxinen_US
dc.date.accessioned2006-09-08T19:18:55Z
dc.date.available2006-09-08T19:18:55Z
dc.date.issued2002-10en_US
dc.identifier.citationSun, Duxin; Lennernas, Hans; Welage, Lynda S.; Barnett, Jeffery L.; Landowski, Christopher P.; Foster, David; Fleisher, David; Lee, Kyung-Dall; Amidon, Gordon L.; (2002). "Comparison of Human Duodenum and Caco-2 Gene Expression Profiles for 12,000 Gene Sequences Tags and Correlation with Permeability of 26 Drugs." Pharmaceutical Research 19(10): 1400-1416. <http://hdl.handle.net/2027.42/41490>en_US
dc.identifier.issn0724-8741en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41490
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12425456&dopt=citationen_US
dc.description.abstractPurpose . To compare gene expression profiles and drug permeability differences in Caco-2 cell culture and human duodenum.en_US
dc.format.extent1034077 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherTransporteren_US
dc.subject.otherPermeabilityen_US
dc.subject.otherGene Expressionen_US
dc.subject.otherMedical Lawen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherGeneChip ®en_US
dc.subject.otherBiomedicineen_US
dc.subject.otherPharmacyen_US
dc.subject.otherIn Vivo/In Vitro Correlationen_US
dc.titleComparison of Human Duodenum and Caco-2 Gene Expression Profiles for 12,000 Gene Sequences Tags and Correlation with Permeability of 26 Drugsen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109; Department of Biopharmaceutics and Stability, Pharmaceutical Research Institute, Bristol-Myers Squibb Company, New Brunswick, New Jersey, 08903en_US
dc.contributor.affiliationumDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationumDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationotherDepartment of Pharmacy, Group of Biopharmaceutics, Uppsala University, Box 580, S-751 23, Uppsala, Swedenen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid12425456en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41490/1/11095_2004_Article_450750.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1020483911355en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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