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Mitochondrial function after global cardiac ischemia and reperfusion: Influences of organelle isolation protocols

dc.contributor.authorKirsh, Marvin M.en_US
dc.contributor.authorLucchesi, Benedict Roberten_US
dc.contributor.authorShlafer, Marshalen_US
dc.contributor.authorWarren, S.en_US
dc.contributor.authorSlater, A. D.en_US
dc.date.accessioned2006-09-08T19:35:29Z
dc.date.available2006-09-08T19:35:29Z
dc.date.issued1981-05en_US
dc.identifier.citationShlafer, M.; Kirsh, M.; Lucchesi, B. R.; Slater, A. D.; Warren, S.; (1981). "Mitochondrial function after global cardiac ischemia and reperfusion: Influences of organelle isolation protocols." Basic Research in Cardiology 76(3): 250-266. <http://hdl.handle.net/2027.42/41745>en_US
dc.identifier.issn0300-8428en_US
dc.identifier.issn1435-1803en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41745
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6791632&dopt=citationen_US
dc.description.abstractDog hearts were made globally ischemic for 1 hr at normothermia, at 28°C, or at normothermia after perfusion with a hyperkalemic cardioplegia solution. After 1 hr of reperfusion mitochondria were isolated from each heart using three protocols involving: processing (homogenization and centrifugation) exclusively in KCl, Tris-EDTA plus albumin (KEA) solution; homogenizing in KEA but washing mitochondria in EDTA-depleted media (KA); or processing exclusively in EDTA-free medium.en_US
dc.format.extent988849 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSteinkopff-Verlag; Dr. Dietrich Steinkopff Verlag ; Springer Science+Business Mediaen_US
dc.subject.otherMitochondriaen_US
dc.subject.otherCardioplegiaen_US
dc.subject.otherHypothermiaen_US
dc.subject.otherMyocardiumen_US
dc.subject.otherGlobal Ischemiaen_US
dc.subject.otherHearten_US
dc.subject.otherOxidative Phosphorylationen_US
dc.subject.otherMedicine & Public Healthen_US
dc.subject.otherCardiologyen_US
dc.titleMitochondrial function after global cardiac ischemia and reperfusion: Influences of organelle isolation protocolsen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelOncology and Hematologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmacology, The University of Michigan Medical School, M6322 Medical Sciences Building I, 48109, Ann Arbor, Michigan, USA; Department of Surgery, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USA; Department of The Upjohn Center for Clinical Pharmacology, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Pharmacology, The University of Michigan Medical School, M6322 Medical Sciences Building I, 48109, Ann Arbor, Michigan, USA; Department of Surgery, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USA; Department of The Upjohn Center for Clinical Pharmacology, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Pharmacology, The University of Michigan Medical School, M6322 Medical Sciences Building I, 48109, Ann Arbor, Michigan, USA; Department of Surgery, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USA; Department of The Upjohn Center for Clinical Pharmacology, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Pharmacology, The University of Michigan Medical School, M6322 Medical Sciences Building I, 48109, Ann Arbor, Michigan, USA; Department of Surgery, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USA; Department of The Upjohn Center for Clinical Pharmacology, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Pharmacology, The University of Michigan Medical School, M6322 Medical Sciences Building I, 48109, Ann Arbor, Michigan, USA; Department of Surgery, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USA; Department of The Upjohn Center for Clinical Pharmacology, The University of Michigan Medical School, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid6791632en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41745/1/395_2005_Article_BF01907770.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF01907770en_US
dc.identifier.sourceBasic Research in Cardiologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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