Stabilized potentiometric solid-state polyion sensors using silver-calixarene complexes as additives within ion-exchanger-based polymeric films
dc.contributor.author | Meyerhoff, Mark E. | en_US |
dc.contributor.author | Lutze, Oliver | en_US |
dc.contributor.author | Hower, Robert W. | en_US |
dc.contributor.author | Ramamurthy, Narayanan | en_US |
dc.contributor.author | Meruva, Ravi K. | en_US |
dc.contributor.author | Frielich, Aaron | en_US |
dc.contributor.author | Brown, Richard B. | en_US |
dc.date.accessioned | 2006-09-08T19:51:05Z | |
dc.date.available | 2006-09-08T19:51:05Z | |
dc.date.issued | 1999-05 | en_US |
dc.identifier.citation | Lutze, Oliver; Meruva, Ravi K.; Frielich, Aaron; Ramamurthy, Narayanan; Brown, Richard B.; Hower, Robert; Meyerhoff, M. E.; (1999). "Stabilized potentiometric solid-state polyion sensors using silver-calixarene complexes as additives within ion-exchanger-based polymeric films." Fresenius' Journal of Analytical Chemistry 364 (1-2): 41-47. <http://hdl.handle.net/2027.42/41988> | en_US |
dc.identifier.issn | 0937-0633 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/41988 | |
dc.description.abstract | Novel solid-state sensors for biomedically important polyions (i.e., heparin and protamine) that exhibit significantly enhanced initial EMF stability are prepared by incorporation of lipophilic silver-calixarene complexes along with the required ion-exchangers within polymeric films. A dithioether of tertiary butyl calix[4]arene together with its silver complex are added to the polyion sensing membranes which are deposited on a silver-epoxy conductor of a solid-state transducer. The silver-complex serves as a reversible electron transfer agent between the organic polymer film and the underlying solid-state conductor, resulting in highly reproducible starting EMF values and improved initial signal stability. This approach is further employed to devise a heparin sensing cartridge for blood measurements based on a novel differential measurement mode. One sensor responds to heparin, while the second identical solid-state sensor serves as a pseudo reference electrode with all heparin present in the sample within this half-cell complexed by the addition of excess protamine. The cartridges are evaluated by monitoring heparin response in spiked dog blood using poly(vinyl chloride) (PVC) blends and fluorinated silicone rubber (Dow Corning RTV 730) films containing appropriate levels of ion-exchanger and Ag + -calixarene/free calixarene additives. | en_US |
dc.format.extent | 101685 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag; Springer-Verlag Berlin Heidelberg | en_US |
dc.subject.other | Legacy | en_US |
dc.title | Stabilized potentiometric solid-state polyion sensors using silver-calixarene complexes as additives within ion-exchanger-based polymeric films | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Materials Science and Engineering | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Electrical Engineering and Computer Science, The University of Michigan, Ann Arbor, MI 48109-2122, USA, US | en_US |
dc.contributor.affiliationum | Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055, USA, US | en_US |
dc.contributor.affiliationum | Department of Electrical Engineering and Computer Science, The University of Michigan, Ann Arbor, MI 48109-2122, USA, US | en_US |
dc.contributor.affiliationum | Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055, USA, US | en_US |
dc.contributor.affiliationum | Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055, USA, US | en_US |
dc.contributor.affiliationum | Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055, USA, US | en_US |
dc.contributor.affiliationum | Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109-1055, USA, US | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/41988/1/216-364-1-2-41_93640041.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/s002160051298 | en_US |
dc.identifier.source | Fresenius' Journal of Analytical Chemistry | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.