Visual evoked cortical potential can be used to differentiate between uncorrected refractive error and macular disorders
dc.contributor.author | Perlman, Ido | en_US |
dc.contributor.author | Segev, Eitan | en_US |
dc.contributor.author | Mazawi, Nael | en_US |
dc.contributor.author | Merhav-Armon, Tamar | en_US |
dc.contributor.author | Lei, Bo | en_US |
dc.contributor.author | Leibu, Rina | en_US |
dc.date.accessioned | 2006-09-08T20:32:24Z | |
dc.date.available | 2006-09-08T20:32:24Z | |
dc.date.issued | 2001-01 | en_US |
dc.identifier.citation | Perlman, Ido; Segev, Eitan; Mazawi, Nael; Merhav-Armon, Tamar; Lei, Bo; Leibu, Rina; (2001). "Visual evoked cortical potential can be used to differentiate between uncorrected refractive error and macular disorders." Documenta Ophthalmologica 102(1): 41-62. <http://hdl.handle.net/2027.42/42621> | en_US |
dc.identifier.issn | 0012-4486 | en_US |
dc.identifier.issn | 1573-2622 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/42621 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=11475365&dopt=citation | en_US |
dc.description.abstract | The visual evoked cortical potential (VECP) is widely used to verify complaints of reduced visual performance and to identify the site of the disorder. In this study, we investigated the correlation between reduced visual acuity and VECP in volunteers with normal corrected visual acuity and in patients suffering from inherited macular degeneration or from age related macular degeneration (ARMD). Flash evoked VECP was not affected by the visual acuity in the cases of refractive error and in ARMD patients but was reduced in amplitude and delayed in implicit time in the patients suffering from inherited macular degeneration. The VECP elicited by pattern reversal checkerboard (PVECP) was not affected by the quality of the visual image in volunteers with uncorrected refractive error when checks of 60′ or larger were used but were considerably reduced in size and prolonged in implicit time for checks smaller than 15′. In both groups of patients suffering from macular dysfunction, pattern reversal VECP was very subnormal and was characterized by prolonged implicit time compared to values expected from their visual acuity. These findings indicate that the PVECP does not directly correlate with visual acuity but rather with foveal function. Therefore, we suggest that recordings of PVECP can be used to differentiate between refractive error and macular disorders as causing reduction in visual acuity when other clinical signs are missing or not available. | en_US |
dc.format.extent | 1345092 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers; Springer Science+Business Media | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.subject.other | Ophthalmology | en_US |
dc.subject.other | Age Related Macular Degeneration | en_US |
dc.subject.other | Refractive Error | en_US |
dc.subject.other | Stargardt's Disease | en_US |
dc.subject.other | Visual Evoked Cortical Potential | en_US |
dc.subject.other | Visual Acuity | en_US |
dc.title | Visual evoked cortical potential can be used to differentiate between uncorrected refractive error and macular disorders | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Opthalmology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, and the Rappaport Institute, Haifa, Israel; W.K. Kellogg Eye Institute, University of Michigan, Ann Arbor, MI, 48105, USA | en_US |
dc.contributor.affiliationother | The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, and the Rappaport Institute, Haifa, Israel | en_US |
dc.contributor.affiliationother | Department of Ophthalmology, Carmel Hospital, Haifa | en_US |
dc.contributor.affiliationother | Department of Ophthalmology, Haemek Medical Center, Afula | en_US |
dc.contributor.affiliationother | Department of Ophthalmology, Bnei-Zion Medical Center, Haifa, Israel | en_US |
dc.contributor.affiliationother | The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, and the Rappaport Institute, Haifa, Israel | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 11475365 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/42621/1/10633_2004_Article_336241.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1023/A:1017539308389 | en_US |
dc.identifier.source | Documenta Ophthalmologica | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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