Microtubule inhibitors block the morphological changes induced in Drosophila blood cells by a parasitoid wasp factor
dc.contributor.author | Rizki, Rose M. | en_US |
dc.contributor.author | Rizki, Tahir M. | en_US |
dc.date.accessioned | 2006-09-08T20:45:53Z | |
dc.date.available | 2006-09-08T20:45:53Z | |
dc.date.issued | 1990-03 | en_US |
dc.identifier.citation | Rizki, R. M.; Rizki, T. M.; (1990). "Microtubule inhibitors block the morphological changes induced in Drosophila blood cells by a parasitoid wasp factor." Experientia 46(3): 311-315. <http://hdl.handle.net/2027.42/42825> | en_US |
dc.identifier.issn | 0014-4754 | en_US |
dc.identifier.issn | 1420-9071 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/42825 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2311722&dopt=citation | en_US |
dc.description.abstract | The shape change of Drosophila melanogaster blood cells (lamellocytes) from discoidal to bipolar that is caused by a factor from the female parasitoid Leptopilina heterotoma is blocked by the tubulin inhibitors vinblastine and vincristine in vitro. The actin inhibitor, cytochalasin B, causes arborization of Drosophila lamellocytes and acts synergistically with the wasp factor to alter lamellocyte morphology. Lamellocyte arborization induced by cytochalasin B is blocked by simultaneous treatment with vinblastine. These observations indicate that the changes in lamellocyte shape induced by both the wasp factor and cytochalasin B require microtubule assembly. | en_US |
dc.format.extent | 1903908 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Birkhäuser-Verlag; Birkhäuser Verlag ; Springer Science+Business Media | en_US |
dc.subject.other | Life Sciences | en_US |
dc.subject.other | Biomedicine General | en_US |
dc.subject.other | Life Sciences, General | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | Cell Biology | en_US |
dc.subject.other | Drosophila Melanogaster | en_US |
dc.subject.other | Leptopilina Heterotoma | en_US |
dc.subject.other | Parasitoid | en_US |
dc.subject.other | Blood Cells | en_US |
dc.subject.other | Vinblastine | en_US |
dc.subject.other | Vincristine | en_US |
dc.subject.other | Cytochalasin B | en_US |
dc.subject.other | Cytoskeleton | en_US |
dc.title | Microtubule inhibitors block the morphological changes induced in Drosophila blood cells by a parasitoid wasp factor | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbsecondlevel | Science (General) | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biology, The University of Michigan, 48109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Biology, The University of Michigan, 48109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 2311722 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/42825/1/18_2005_Article_BF01951775.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF01951775 | en_US |
dc.identifier.source | Experientia | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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