Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp
dc.contributor.author | Shreffler, Donald C. | en_US |
dc.contributor.author | Hansen, Ted H. | en_US |
dc.contributor.author | Krasteff, T. N. | en_US |
dc.date.accessioned | 2006-09-11T14:19:03Z | |
dc.date.available | 2006-09-11T14:19:03Z | |
dc.date.issued | 1974-10 | en_US |
dc.identifier.citation | Hansen, T. H.; Krasteff, T. N.; Shreffler, D. C.; (1974). "Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp." Biochemical Genetics 12(4): 281-293. <http://hdl.handle.net/2027.42/44121> | en_US |
dc.identifier.issn | 1573-4927 | en_US |
dc.identifier.issn | 0006-2928 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/44121 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4216347&dopt=citation | en_US |
dc.description.abstract | A radial immunodiffusion assay for quantitation of the Ss and Slp serum antigens is described. Significant differences between the mean serum concentrations of Ss and Slp were found among various inbred strains. Some of these differences have been shown to be associated with the H-2 haplotype. The quantitative difference between Slp levels associated with the H-2 a and H-2 S haplotypes has been used as a marker for the S region in the analysis of certain H-2 recombinant strains [A.TH, B10.S(7R), B10.S(9R), and B10.BSVS]. Male mice of two strains with the H-2 b haplotype have been shown to have significantly lower levels of Ss compared to males of the other strains tested. Male mice of every strain examined were found to have significantly higher levels of Ss in their serum than females of the same strain. The molecular relationship and developmental patterns of the Ss and Slp antigens have also been investigated using the radial immunodiffusion assay. | en_US |
dc.format.extent | 686821 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media | en_US |
dc.subject.other | Histocompatibility-2 Locus ( H-2 ) | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Human Genetics | en_US |
dc.subject.other | Medical Microbiology | en_US |
dc.subject.other | Zoology | en_US |
dc.subject.other | Mouse Inbred Strains | en_US |
dc.subject.other | Radial Immunodiffusion | en_US |
dc.subject.other | Serum Antigens Ss, Slp | en_US |
dc.title | Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Human Genetics, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 4216347 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/44121/1/10528_2004_Article_BF00485949.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00485949 | en_US |
dc.identifier.source | Biochemical Genetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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