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Glycosaminoglycan accumulation with partial deficiency of β-glucuronidase in the C3H strain of mice

dc.contributor.authorSandman, Roberten_US
dc.contributor.authorYatziv, Shaulen_US
dc.contributor.authorErickson, Robert P.en_US
dc.contributor.authorRobertson, William van B.en_US
dc.date.accessioned2006-09-11T14:19:39Z
dc.date.available2006-09-11T14:19:39Z
dc.date.issued1978-12en_US
dc.identifier.citationYatziv, Shaul; Erickson, Robert P.; Sandman, Robert; Robertson, William van B.; (1978). "Glycosaminoglycan accumulation with partial deficiency of β-glucuronidase in the C3H strain of mice." Biochemical Genetics 16 (11-12): 1079-1084. <http://hdl.handle.net/2027.42/44128>en_US
dc.identifier.issn0006-2928en_US
dc.identifier.issn1573-4927en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/44128
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=109077&dopt=citationen_US
dc.description.abstractYoung (60–80 days) mice of the low β-glucuronidase strain, C3H/HeJ, showed no differences in hepatic levels of glycosaminoglycans (GAGs) when compared to the randombred, “normal” Swiss-Webster mice of the same age. However, by 12 months of age hepatic GAG is nearly twice as high in C3H/HeJ mice as in Swiss-Webster mice. Studies of β-glucuronidase, β-galactosidase, and N -acetyl-β-glucosaminidase in four tissues of the two types of mice at the two ages revealed that glucuronidase was the only enzyme with lower activity in the C3H/HeJ strain.en_US
dc.format.extent313901 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherGlycosaminoglycansen_US
dc.subject.otherHuman Geneticsen_US
dc.subject.otherMedical Microbiologyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherβ-Glucuronidaseen_US
dc.subject.otherLysosomal Enzymesen_US
dc.subject.otherMucopolysaccharidosisen_US
dc.subject.otherMiceen_US
dc.subject.otherZoologyen_US
dc.titleGlycosaminoglycan accumulation with partial deficiency of β-glucuronidase in the C3H strain of miceen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pediatrics, University of California, 94143, San Francisco, California; Department of Human Genetics, University of Michigan Medical School, 48109, Ann Arbor, Michiganen_US
dc.contributor.affiliationotherDepartment of Pediatrics, University of California, 94143, San Francisco, California; Department of Ophthalmology, University of California, 94143, San Francisco, Californiaen_US
dc.contributor.affiliationotherChildren's Hospital at Stanford, Department of Pediatrics, Stanford University School of Medicine, 94305, Stanford, Californiaen_US
dc.contributor.affiliationotherDepartment of Pediatrics, University of California, 94143, San Francisco, California; Department of Pediatrics, Hadassah Medical Organization, Kiryat Hadassah, Jerusalem, Israelen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid109077en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/44128/1/10528_2004_Article_BF00484528.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00484528en_US
dc.identifier.sourceBiochemical Geneticsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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