Glycosaminoglycan accumulation with partial deficiency of β-glucuronidase in the C3H strain of mice
dc.contributor.author | Sandman, Robert | en_US |
dc.contributor.author | Yatziv, Shaul | en_US |
dc.contributor.author | Erickson, Robert P. | en_US |
dc.contributor.author | Robertson, William van B. | en_US |
dc.date.accessioned | 2006-09-11T14:19:39Z | |
dc.date.available | 2006-09-11T14:19:39Z | |
dc.date.issued | 1978-12 | en_US |
dc.identifier.citation | Yatziv, Shaul; Erickson, Robert P.; Sandman, Robert; Robertson, William van B.; (1978). "Glycosaminoglycan accumulation with partial deficiency of β-glucuronidase in the C3H strain of mice." Biochemical Genetics 16 (11-12): 1079-1084. <http://hdl.handle.net/2027.42/44128> | en_US |
dc.identifier.issn | 0006-2928 | en_US |
dc.identifier.issn | 1573-4927 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/44128 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=109077&dopt=citation | en_US |
dc.description.abstract | Young (60–80 days) mice of the low β-glucuronidase strain, C3H/HeJ, showed no differences in hepatic levels of glycosaminoglycans (GAGs) when compared to the randombred, “normal” Swiss-Webster mice of the same age. However, by 12 months of age hepatic GAG is nearly twice as high in C3H/HeJ mice as in Swiss-Webster mice. Studies of β-glucuronidase, β-galactosidase, and N -acetyl-β-glucosaminidase in four tissues of the two types of mice at the two ages revealed that glucuronidase was the only enzyme with lower activity in the C3H/HeJ strain. | en_US |
dc.format.extent | 313901 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Glycosaminoglycans | en_US |
dc.subject.other | Human Genetics | en_US |
dc.subject.other | Medical Microbiology | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | β-Glucuronidase | en_US |
dc.subject.other | Lysosomal Enzymes | en_US |
dc.subject.other | Mucopolysaccharidosis | en_US |
dc.subject.other | Mice | en_US |
dc.subject.other | Zoology | en_US |
dc.title | Glycosaminoglycan accumulation with partial deficiency of β-glucuronidase in the C3H strain of mice | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pediatrics, University of California, 94143, San Francisco, California; Department of Human Genetics, University of Michigan Medical School, 48109, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationother | Department of Pediatrics, University of California, 94143, San Francisco, California; Department of Ophthalmology, University of California, 94143, San Francisco, California | en_US |
dc.contributor.affiliationother | Children's Hospital at Stanford, Department of Pediatrics, Stanford University School of Medicine, 94305, Stanford, California | en_US |
dc.contributor.affiliationother | Department of Pediatrics, University of California, 94143, San Francisco, California; Department of Pediatrics, Hadassah Medical Organization, Kiryat Hadassah, Jerusalem, Israel | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 109077 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/44128/1/10528_2004_Article_BF00484528.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00484528 | en_US |
dc.identifier.source | Biochemical Genetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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