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Intestinal intraepithelial lymphocyte derived angiotensin converting enzyme modulates epithelial cell apoptosis

dc.contributor.authorWildhaber, Barbara E.en_US
dc.contributor.authorYang, H.en_US
dc.contributor.authorHaxhija, Emir Q.en_US
dc.contributor.authorSpencer, Ariel U.en_US
dc.contributor.authorTeitelbaum, Daniel H.en_US
dc.date.accessioned2006-09-11T14:40:51Z
dc.date.available2006-09-11T14:40:51Z
dc.date.issued2005-12en_US
dc.identifier.citationWildhaber, B. E.; Yang, H.; Haxhija, E. Q.; Spencer, A. U.; Teitelbaum, D. H.; (2005). "Intestinal intraepithelial lymphocyte derived angiotensin converting enzyme modulates epithelial cell apoptosis." Apoptosis 10(6): 1305-1315. <http://hdl.handle.net/2027.42/44361>en_US
dc.identifier.issn1360-8185en_US
dc.identifier.issn1573-675Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/44361
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=16215678&dopt=citationen_US
dc.description.abstractBackground & Aims : Intestinal adaptation in short bowel syndrome (SBS) consists of increased epithelial cell (EC) proliferation as well as apoptosis. Previous microarray analyses of intraepithelial lymphocytes (IEL) gene expression after SBS showed an increased expression of angiotensin converting enzyme (ACE). Because ACE has been shown to promote alveolar EC apoptosis, we examined if IEL-derived ACE plays a role in intestinal EC apoptosis.en_US
dc.format.extent696153 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers; Springer Science + Business Media, Inc.en_US
dc.subject.otherMedicine & Public Healthen_US
dc.subject.otherCancer Researchen_US
dc.subject.otherVirologyen_US
dc.subject.otherOncologyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherCell Biologyen_US
dc.subject.otherAngiotensin Converting Enzymeen_US
dc.subject.otherApoptosisen_US
dc.subject.otherEpithelial Cellsen_US
dc.subject.otherIntraepithelial Lymphocytesen_US
dc.subject.otherTumor Necrosis Factor Alphaen_US
dc.titleIntestinal intraepithelial lymphocyte derived angiotensin converting enzyme modulates epithelial cell apoptosisen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelRadiologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Surgery, Section of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Surgery, Section of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Surgery, Section of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Surgery, Section of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Surgery, Section of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USA; Department of Surgery, Section of Pediatric Surgery, University of Michigan Hospitals, Mott F3970, Box 0245, Ann Arbor, MI, 48109, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid16215678en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/44361/1/10495_2005_Article_2138.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/s10495-005-2138-yen_US
dc.identifier.sourceApoptosisen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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