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Rapid equilibration of warfarin between rat tissue and plasma

dc.contributor.authorWagner, John G.en_US
dc.contributor.authorBenya, Theodore J.en_US
dc.date.accessioned2006-09-11T15:37:35Z
dc.date.available2006-09-11T15:37:35Z
dc.date.issued1975-08en_US
dc.identifier.citationBenya, Theodore J.; Wagner, John G.; (1975). "Rapid equilibration of warfarin between rat tissue and plasma." Journal of Pharmacokinetics and Biopharmaceutics 3(4): 237-255. <http://hdl.handle.net/2027.42/45061>en_US
dc.identifier.issn0090-466Xen_US
dc.identifier.issn1573-8744en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/45061
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1185522&dopt=citationen_US
dc.description.abstractPlasma and tissue concentrations of warfarin in the rat were measured as a function of time following a 10 mg/kg intravenous dose. The mathematical interpretation of the experimental results suggested that the data could be explained in terms of a two-compartment open model. Following equilibration, which occurred within a few minutes after injection, individual tissue levels and plasma levels of warfarin were found to be always directly proportional .en_US
dc.format.extent857753 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherPharmacyen_US
dc.subject.otherTissue Bindingen_US
dc.subject.otherWarfarinen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherTissue Distributionen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherVeterinary Medicineen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherLinear Pharmacokineticsen_US
dc.subject.otherPlasma Protein Bindingen_US
dc.titleRapid equilibration of warfarin between rat tissue and plasmaen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCollege of Pharmacy and Upjohn Center for Clinical Pharmacology, University of Michigan, 48104, Ann Arbor, Michiganen_US
dc.contributor.affiliationotherCollege of Pharmacy, Ohio Northern University, 45810, Ada, Ohioen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid1185522en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/45061/1/10928_2005_Article_BF01066920.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF01066920en_US
dc.identifier.sourceJournal of Pharmacokinetics and Biopharmaceuticsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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